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Perspective | Open Access

Food and Medicine Homology Focus in 2026

Meng-Yao Li1, Gui-Fen Wu2, Feng Lu3, Cong Geng4, Song Yu5, Ming-Liang Gao6, Yan Gao7,8, Xing-Fang Zhang9, Jia-Wei Ling10, Dong-Li Li11, Zhen-Xing Wang12, Qiang Ren13, Ze-Lin Li14, Ning-Xian Yang15, Hong-Cai Li16, Shao-Jie Yang17, Qian Zhang18, Jun Li18, Wen-Long Sun19, Cheng-Hao Lv20, Jun-Ping Zheng21, Ji Li22, Gui-Li Yang23, Bo-Ran Zhu24, Tao Zhuang25, Zhong-Yang Ren26, Li Tao27, Yang Lin28, Muhammad Waheed Iqbal28, Hao-Zhou Huang29, Tian-Liang Liu30, Han-Qing Pang31,32, Jing-Yu Xu33, Jin Zhang15, Xuan Jiang34, Jun Li35, Tao Jin36, Zhan-Dong Yang37, Hui-Hui Su38, Lei Tian39, Ye Li40, Xiao-Yu Liu22, Qian-Qian Yao41, Wen-Yi Kang42,43 ( )
State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200017, China
Guangxi Minzu Normal University, Chongzuo 532200, China
Institute of Agri-food Processing and Nutrition, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China
Department of Clinical Laboratory, The Second Hospital of Dalian Medical University, Dalian 116027, China
NHC Specialty Laboratory of Food Safety Risk Assessment and Standard Development, Division of Chemical Toxicity and Safety Assessment, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 201107, China
Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210046, China
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China
College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
School of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529020, China
College of Biological Science and Food Engineering, Southwest Forestry University, Kunming 650224, China
Department of Pharmacy, Jining Medical University, Rizhao 276826, China
Agro-Products Processing Research Institute, Yunnan Academy of Agricultural Sciences, Kunming 650223, China
State Key Laboratory of Discovery and Utilization of functional Components in Traditional Chinese Medicine, School of Public Health, Guizhou Medical University, Guiyang 561113, China
College of Food Science and Engineering, Northwest A & F University, Yangling712100, China
The Second Affiliation Hospital of Anhui University of Chinese Medicine, Hefei 230061, China
College of Pharmacy, Inner Mongolia Medical University, Hohhot 010110, China
School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China
Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410000, China
School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, China
Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin 150001, China
College of Life Sciences, Guizhou University, Guiyang 550025, China
Nanjing University of Chinese Medicine, Nanjing 210023, China
School of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China
College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China
College of Food and Health, Zhejiang A & F University, Hangzhou 311300, China
College of Food Science, Zhejiang University of Technology, Hangzhou 310014, China
School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
Zhoukou Hospital of TCM, Zhoukou 466000, China
School of Traditional Chinese Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, China
Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control, Yangzhou University, Yangzhou 225009, China
College of Materials Science and Engineering, Qiqihar University, Qiqihar 161006, China
State Key Laboratory of Food Nutrition and Safety, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China
Food Microbiology Key Laboratory of Sichuan Province, College of Food and Bioengineering, Xihua University, Chengdu 610039, China
Department of Food Biology, Anhui Vocational College of Grain Engineering, Hefei 230011, China
Guangzhou National Laboratory, Guangzhou 510005, China
Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China
Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China
School of Basic Medicine, Kunming University of Science and Technology, Kunming 650500, China
College of Basic Medical Science, China Three Gorges University, Yichang 443000, China
National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng 475004, China
Joint International Research Laboratory of Food & Medicine Resource Function, Henan University, Kaifeng 475004, China
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Highlights

(1) Driving a paradigm shift in the food and medicine homology field from traditional experience-based practices to a scientific, systematic, and precise methodology.

(2) Advocating for a paradigm shift in mechanistic research, moving away from simple linear models towards an integrated comprehension of intricate biological networks and systems biology.

(3) Developing a novel proactive health management system with dynamic individual data, incorporating real-time optimization and adaptive adjustment features.

(4) Facilitating the intelligent and eco-friendly upgrade of the entire industrial chain from raw material innovation to ecological construction, by integrating advanced technologies.

(5) Elevating the provision of health products by integrating lifestyle, cultural experiences, and synergistic ecosystem into comprehensive health solutions.

Graphical Abstract

This perspective systematically outlines the developmental framework for food and medicine homology in 2026. It begins with establishing a foundation of trust and standardization as cornerstone, including scientific expansion of substance list, comprehensive standards and safety control across the entire chain, and the construction of high-level evidence. The materials basis and related mechanisms are elucidated through fundamental elements such as precise identification of active components, gut microbiota interaction mechanisms, and discovery of non-classical mechanisms. At the application level, personalized data and AI platforms are constructed to develop precision nutrition intervention strategies targeting chronic diseases and the entire life cycle. Emerging resource exploration, scenario-based product development, and sustainable industrial ecosystem construction are achieved through translational research. Key technologies such as AI-driven revolution, smart nano delivery systems, synthetic biology, and green processing are driven by cutting-edge innovations. Finally, interdisciplinary integration expands into fields including neuroscience, health-preserving cultural tourism, and traditional knowledge mining, forming a complete closed-loop system from scientific foundations to industrial and societal value realization.

References

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Food & Medicine Homology
Volume 3 Issue 2,
June 2026
Article number: 9420133
DOI: 10.26599/FMH.2026.9420133

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Cite this article:
Li M-Y, Wu G-F, Lu F, et al. Food and Medicine Homology Focus in 2026. Food & Medicine Homology, 2026, 3(2): 9420133. https://doi.org/10.26599/FMH.2026.9420133

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Received: 15 December 2025
Revised: 22 December 2025
Accepted: 22 December 2025
Published: 31 December 2025
© National R & D Center for Edible Fungus Processing Technology 2026. Published by Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).