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Original Article | Open Access

Relationship between neurotic personality and depression: mediating effects of maladaptive emotion regulation strategies and anxiety

Xiaoyi Chen1Yufei Wang1Lunjie Chen2Yuan Liu3Xing Wang4Liping Huang3Mingting Wang5( )Mengqian Li3( )
The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi, China
Department of Psychology, School of Public Policy and Management, Nanchang University, Nanchang 330006, Jiangxi, China
Department of Psychosomatic Medicine, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi, China
Clinical Medical Experiment Center, Nanchang University, Nanchang 330006, Jiangxi, China
Psychiatric Rehabilitation Department, Affiliated Mental Health Center of Kunming Medical University, Kunming 650500, Yunnan, China
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Abstract

Introduction

Depression is a prevalent psychological problem among higher vocational college students. This study aimed to explore the potential relationships among neurotic personality, maladaptive emotion regulation strategies, anxiety, and depressive symptoms in higher vocational college students.

Methods

Higher vocational college students in Jiangxi, China, were recruited for this survey study. The Chinese version of the Eysenck Personality Questionnaire, the Cognitive Emotion Regulation Questionnaire, the Self‐assessment Scale of Anxiety, and the Self‐depression Scale were administered to assess the mental condition of the students. We used serial mediation models to understand whether maladaptive emotion regulation strategies and anxiety mediate the effect of neurotic personality on depression.

Results

Neurotic personality was significantly positively correlated with depression severity (r = 0.52, p < 0.001). Furthermore, catastrophizing (total mediating effect: 1.002) and blame‐other strategies (total mediating effect: 0.993), as maladaptive emotion regulation strategies, and anxiety exerted a chain mediating effect on the relationship between neurotic personality and depression.

Conclusion

This study revealed the significant effect of neurotic personality on depression in higher vocational college students and its underlying mechanism. Our results may be valuable for maintaining and improving the physical and mental health of higher vocational college students.

References

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Brain Science Advances
Article number: 905014

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Cite this article:
Chen X, Wang Y, Chen L, et al. Relationship between neurotic personality and depression: mediating effects of maladaptive emotion regulation strategies and anxiety. Brain Science Advances, 2026, 12(2): 905014. https://doi.org/10.26599/BSA.2026.905014

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Received: 27 March 2026
Accepted: 31 March 2026
Published: 18 June 2026
© The authors 2026.

This article is published with open access at journals.sagepub.com/home/BSA Creative Commons CC BY: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage)