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Original Article | Open Access

A pilot study examining the effects of transcranial direct current stimulation on cognitive and visual impairments

Michael Chih Chien Kuo1( ), Armstrong Tat San Chiu2
School of Medical and Health Sciences, Tung Wah College, Hong Kong, China
The Hong Kong Society for the Blind, Hong Kong, China
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Abstract

Objective

The study aimed to assess the impact of a single session of transcranial direct current stimulation (tDCS) on people with both cognitive and visual impairments.

Methods

Sixteen individuals with visual and cognitive impairments were recruited and randomized to either the experimental or sham group. While the sham group only received 30 seconds of initial stimulation, participants in the experimental group received an active tDCS intervention for 20 minutes. The Cantonese Mini‐Mental State Examination (CMMSE), the Digit Span Forward Test, the Chinese Verbal Learning Test (CVVLT), and the memory subtest from the Neurobehavioral Cognitive Status Examination (NCSE) were the neuropsychological assessments. To ascertain whether there are statistical differences between groups, repeated measures ANOVA was used to analyze data gathered prior to and following the intervention.

Results

Age, educational attainment, and baseline CMMSE scores did not significantly differ between the groups. The type of stimulation and CVVLT total scores showed a significant interaction effect, with improvements in scores seen after active tDCS treatment. Other measured variables did not show any additional effects that were statistically significant.

Conclusion

These findings provided preliminary support for the potential efficacy of tDCS in improving immediate memory functions among individuals with both cognitive and visual deficits.

References

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Brain Science Advances
Article number: 905007

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Cite this article:
Kuo MCC, Chiu ATS. A pilot study examining the effects of transcranial direct current stimulation on cognitive and visual impairments. Brain Science Advances, 2025, 11(4): 905007. https://doi.org/10.26599/BSA.2025.905007

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Received: 20 February 2025
Revised: 08 March 2025
Accepted: 03 June 2025
Published: 27 January 2026
© The authors 2025.

This article is published with open access at journals.sagepub.com/home/BSA Creative Commons Non Commercial CC BY‐NC: This article is distributed under the terms of the Creative Commons Attribution‐NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non‐commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).