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Objective:

To explore the usefulness of multishot diffusion tensor imaging (DTI) for evaluating the neurological function of patients with spinal cord tumors

Methods:

Routine magnetic resonance imaging and multishot DTI were performed in five patients with spinal cord tumors. The values of fractional anisotropy (FA) and radial diffusivity (RD) were analyzed.

Results:

Multishot DTI of spinal cord tumors allowed for defining the margins of tumors and determining the relationship of tumors with the adjacent white matter structures of the spinal cord. Multishot DTI demonstrated significantly increased RD and decreased FA of spinal cord tumors compared with those of the normal spinal cord.

Conclusions:

Multishot DTI is a potentially useful modality for differentiating resectable tumors from nonresectable ones based on preoperative imaging alone as well as for differentiating intramedullary tumors from extramedullary ones. Further prospective studies are warranted to confirm these results.


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Application of multishot diffusion tensor imaging in spinal cord tumors

Show Author's information Jiefei Li1Le He2Yuqi Zhang1( )
 Department of Neurosurgery, Yuquan Hospital, Tsinghua University, Beijing 100040, China
 Department of Center for Biomedical Imaging Research, Tsinghua University, Beijing 100084, China

Abstract

Objective:

To explore the usefulness of multishot diffusion tensor imaging (DTI) for evaluating the neurological function of patients with spinal cord tumors

Methods:

Routine magnetic resonance imaging and multishot DTI were performed in five patients with spinal cord tumors. The values of fractional anisotropy (FA) and radial diffusivity (RD) were analyzed.

Results:

Multishot DTI of spinal cord tumors allowed for defining the margins of tumors and determining the relationship of tumors with the adjacent white matter structures of the spinal cord. Multishot DTI demonstrated significantly increased RD and decreased FA of spinal cord tumors compared with those of the normal spinal cord.

Conclusions:

Multishot DTI is a potentially useful modality for differentiating resectable tumors from nonresectable ones based on preoperative imaging alone as well as for differentiating intramedullary tumors from extramedullary ones. Further prospective studies are warranted to confirm these results.

Keywords: magnetic resonance imaging, diffusion tensor imaging (DTI), spinal cord, tumor, multishot DTI

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Publication history
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Publication history

Received: 01 November 2018
Revised: 09 January 2019
Accepted: 02 February 2019
Published: 19 December 2019
Issue date: March 2019

Copyright

© The authors 2019

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This article is published with open access at journals.sagepub.com/home/BSA

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