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Vascular factors to cognitive impairment in degenerative on non-degenerative diseases have been reported, examined, and debated for several decades. The various definitions of cognitive impairment due to vascular origins will make these results diverse. During this review, we are going to report currently update information of vascular contributions to cognitive function, in clinical or neuro-imaging findings. Risks factors and their managements also will be discussed and reported to have a comprehensive review.

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Vascular contribution to cognition in stroke and Alzheimer’s disease

Show Author's information Yuanhan Yang1,2,3( )Jongling Fuh4,5Vincent C. T. Mok6
 Department of Neurology, Kaohsiung Municipal Ta-Tung Hospital, Taiwan, China
 Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan, China
 Department of and Master’s Program in Neurology, Faculty of Medicine, Kaohsiung Medical University, Kaohsiung City 80708, Taiwan, China
 Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, China
 Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, China
 Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China


Vascular factors to cognitive impairment in degenerative on non-degenerative diseases have been reported, examined, and debated for several decades. The various definitions of cognitive impairment due to vascular origins will make these results diverse. During this review, we are going to report currently update information of vascular contributions to cognitive function, in clinical or neuro-imaging findings. Risks factors and their managements also will be discussed and reported to have a comprehensive review.

Keywords: Alzheimer’s disease, vascular cognitive impairment, post stroke dementia, white matter hyperintensity, diabetic mellitus, hypertension


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Publication history
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Publication history

Received: 01 March 2018
Revised: 15 April 2018
Accepted: 08 May 2018
Published: 25 November 2018
Issue date: September 2018


© The authors 2018

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