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Letter | Open Access

Antibiotics and probiotics differentially shape immunotherapy outcomes in non-small cell lung cancer

Shuling Ma1,*, Zijun Zhai1,2,*, Rui Ding1, Shijie Shang1,3, Xinyi Liang1, Shan Yin1,2, Haofeng Lin4, Guomeng Sha1, Ran Zhang1, Jinming Yu1, Qian Song1 ( ), Dawei Chen1,2 ( )
Shandong Provincial Key Laboratory of Precision Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China
Cheeloo College of Medicine, Shandong University Cancer Center, Jinan 250000, China
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430023, China
Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou 510006, China

*These authors contributed equally to this work.

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Cancer Biology & Medicine
Volume 23 Issue 5,
May 2026
Pages 703-716
DOI: 10.20892/j.issn.2095-3941.2025.0844

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Cite this article:
Ma S, Zhai Z, Ding R, et al. Antibiotics and probiotics differentially shape immunotherapy outcomes in non-small cell lung cancer. Cancer Biology & Medicine, 2026, 23(5): 703-716. https://doi.org/10.20892/j.issn.2095-3941.2025.0844

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Received: 11 February 2026
Accepted: 14 April 2026
Published: 29 May 2026
©2026 The Authors.

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