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Original Article | Open Access

Evaluation of an intelligent digital platform for population management in cervical cancer screening

Xinhua Jia1,2,*Chen Gao3,*Xi’ao Da1Jingyi Shi1,2Mingyang Chen1Rufei Duan4Zhifang Li5Ruimei Feng6Yao Yang1Jiahuan Zhai3Hanyue Ding1( )Alex Ng3 ( )Youlin Qiao1,2 ( )
School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China
Tencent Inclusive Health Lab, Beijing 100193, China
Department of Cancer Prevention and Control, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming 650118, China
School of Public Health, Changzhi Medical College, Changzhi 046000, China
School of Public Health, Shanxi Medical University, Jinzhong 030001, China

*These authors contributed equally to this work.

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Abstract

Objective

To describe temporal changes associated with deployment of an optical character recognition (OCR)-enabled One-Identity (One-ID) digital platform for rural cervical cancer screening, focusing on over-screening rates, CIN2+ detection, colposcopy follow-up, and CIN2+ management.

Methods

A multi-county pre-post observational study was conducted in six rural counties in Shanxi, Yunnan, and Sichuan Provinces (2021–2024), encompassing 153,978 encounters. The digital platform integrates OCR identity capture, deterministic One-ID linkage, and real-time duplicate alerts. Over-screening proportions before and after digital deployment were compared, changes in CIN2+ detection rate were evaluated, and colposcopy follow-up and CIN2+ management were assessed. Differences were tested with χ2 or Fisher’s exact tests.

Results

Among 153,978 encounters, the proportion of over-screening decreased from 12.64% in 2023 to 0.17% in 2024 with an absolute reduction of 12.17% (95% CI: 11.94–12.40; P < 0.001). The share of women receiving a first screening within the preceding 3 y increased from 78.3% to 88.2% (P < 0.001). Colposcopy completion improved from 64.1% to 84.9%. The CIN2+ detection rate rose from 0.35% (2021–2023 pooled) to 0.67% in 2024 (P < 0.001) and CIN2+ management completion increased from 56.0% to 76.2% (95% CI: 13.3–27.2; P < 0.001). These improvements were consistent across age groups, counties, and screening strategies.

Conclusions

The OCR-enabled One-ID platform substantially reduced over-screening, increased CIN2+ detection rate, and strengthened case follow-up/management, particularly where baseline tracking was weak, supporting scalable digital reinforcement of rural screening programmes.

References

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Cancer Biology & Medicine
Pages 1068-1082

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Cite this article:
Jia X, Gao C, Da X, et al. Evaluation of an intelligent digital platform for population management in cervical cancer screening. Cancer Biology & Medicine, 2025, 22(9): 1068-1082. https://doi.org/10.20892/j.issn.2095-3941.2025.0419

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Received: 24 July 2025
Accepted: 05 September 2025
Published: 29 September 2025
©2025 The Authors.

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