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Perspective on new cell-free DNA technologies for early cancer detection

Show Author's information Jie Li1,2Xun Lan1,2,3 ( )
Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China
MOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing 100084, China
Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China

References(15)

1

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021; 71: 209-49.

2

Li J, Wang W, Xia P, Wan L, Zhang L, Yu L, et al. Identification of a five-lncRNA signature for predicting the risk of tumor recurrence in patients with breast cancer. Int J Cancer. 2018; 143: 2150-60.

3

Xu C, Qi R, Ping Y, Li J, Zhao H, Wang L, et al. Systemically identifying and prioritizing risk lncRNAs through integration of pan-cancer phenotype associations. Oncotarget. 2017; 8: 12041.

4

Xu H, Li W. Early detection of gastric cancer in China: progress and opportunities. Cancer Biol Med. 2022; 19: 1622-8.

5

Li C, Wang H, Jiang Y, Fu W, Liu X, Zhong R, et al. Advances in lung cancer screening and early detection. Cancer Biol Med. 2022; 19: 591-608.

6

Li J, Xu M, Peng J, Wang J, Zhao Y, Wu W, et al. Novel technologies in cfDNA analysis and potential utility in clinic. Chinese J Cancer Res. 2021; 33: 708.

7

Li J, Sun X, Yang H, Chen J, Bu Z, Ji J, et al. Integrated analysis toolkit for dissecting whole-genome-wide features of cell-free DNA. Clin Transl Med. 2023; 13: e1212.

8

Smyth EC, Nilsson M, Grabsch HI, van Grieken NC, Lordick F. Gastric cancer. Lancet. 2020; 396: 635-48.

9

Sadeh R, Sharkia I, Fialkoff G, Rahat A, Gutin J, Chappleboim A, et al. ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin. Nat Biotechnol. 2021; 39: 586-98.

10

Grunau C, Clark SJ, Rosenthal A. Bisulfite genomic sequencing: systematic investigation of critical experimental parameters. Nucleic Acids Res. 2001; 29: E65-5.

11

Cristiano S, Leal A, Phallen J, Fiksel J, Adleff V, Bruhm DC, et al. Genome-wide cell-free DNA fragmentation in patients with cancer. Nature. 2019; 570: 385-9.

12

Foda ZH, Annapragada AV, Boyapati K, Bruhm DC, Vulpescu NA, Medina JE, et al. Detecting liver cancer using cell-free DNA fragmentomes. Cancer Discov. 2023; 13: 616-31.

13

Ulz P, Thallinger GG, Auer M, Graf R, Kashofer K, Jahn SW, et al. Inferring expressed genes by whole-genome sequencing of plasma DNA. Nat Genet. 2016; 48: 1273-8.

14

Snyder MW, Kircher M, Hill AJ, Daza RM, Shendure J. Cell-free DNA comprises an in vivo nucleosome footprint that informs its tissues-of-origin. Cell. 2016; 164: 57-68.

15

Esfahani MS, Hamilton EG, Mehrmohamadi M, Nabet BY, Alig SK, King DA, et al. Inferring gene expression from cell-free DNA fragmentation profiles. Nat Biotechnol. 2022; 40: 585-97.

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Publication history

Received: 06 May 2023
Accepted: 14 July 2023
Published: 08 August 2023
Issue date: February 2024

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©2024 Cancer Biology & Medicine.

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