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Review

Biology, staging, and treatment of breast cancer during pregnancy: reassessing the evidences

Fedro Alessandro Peccatori1( ), Matteo Lambertini2, Giovanna Scarfone3, Lino Del Pup4, Giovanni Codacci-Pisanelli5
Gynecologic Oncology Department, European Institute of Oncology, Milan 20141, Italy
Department of Medicine, Institut Jules Bordet and Université Libre de Bruxelles (ULB), Brussels 100, Belgium
Department of Obstetrics and Gynecology, IRCCS Ospedale Maggiore Policlinico Mangiagalli, Milan 20121, Italy
Gynecologic Oncology Department, National Cancer Institute, Aviano 3301, Italy
Department of Medical and Surgical Science and Biotechnology, University “la Sapienza”, Rome 00185, Italy
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Abstract

Breast cancer is one of the most frequently diagnosed malignancies during pregnancy. Here, we review the management of women with breast cancer during pregnancy (BCP), focusing on biology, diagnosis and staging, local and systemic treatments, obstetric care and long-term follow-up of children with prenatal exposure to anticancer treatments.

Keywords

Breast cancerpregnancychemotherapyendocrine therapytargeted therapy

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Cancer Biology & Medicine
Volume 15 Issue 1,
February 2018
Pages 6-13
DOI: 10.20892/j.issn.2095-3941.2017.0146

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Peccatori FA, Lambertini M, Scarfone G, et al. Biology, staging, and treatment of breast cancer during pregnancy: reassessing the evidences. Cancer Biology & Medicine, 2018, 15(1): 6-13. https://doi.org/10.20892/j.issn.2095-3941.2017.0146

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Received: 12 October 2017
Accepted: 03 January 2018
Published: 01 February 2018
© 2018 by Cancer Biology & Medicine