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Brain Science Advances 2016, 2(4): 244-251 https://doi.org/10.18679/CN11-6030_R.2016.031
Review Article | Open Access | Issue | Published: 01 December 2016

Management of post-stroke neuropsychiatric disorders

Show Author's Information Ahsan Ali Khan1,  Lukui Chen1( ),  Guilong Zhang1,  Xiaoyuan Guo1,  Guojian Wu1,  Hong Wang1,  Yang You1,  Yuchun Gu2,3,  Yonggui Yuan4
Department of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing 210009, China
Aston Institute of Regenerative Medicine, Aston Medical School, Aston University, Birmingham, UK
Molecular Pharmacology Laboratory, Institute of Molecular Medicine, Peking University, Beijing 100871, China
Department of Psychology, Zhongda Hospital, Southeast University, Nanjing 210009, China
Keywords:
depression, anxiety, post-stroke, neuropsychiatric disorders
Cite this article:
Khan AA, Chen L, Zhang G, et al. Management of post-stroke neuropsychiatric disorders. Brain Science Advances, 2016, 2(4): 244-251. https://doi.org/10.18679/CN11-6030_R.2016.031
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Abstract Full text About this article

Post-stroke neuropsychiatric (NP) disorders are common and have complex etiologies. Multiple factors such as lesion location, personality characteristics, socioeconomic status, pre-stroke psychiatric history, and family support are the determining factors in most cases. Although depression and anxiety are more common, emotional incontinence and catastrophic reactions are also frequently observed. Post-stroke depression (PSD) has been associated with an increased risk of stroke recurrence. Despite its serious consequences and high prevalence, PSD remains undetected and untreated. Treatment options of NP disorders depend on severity, presentation at the time of diagnosis, and patient cooperation, and include antidepressants, mood stabilizers, exercise therapy, psychotherapy, and even revascularization. The efficient management of NP disorders improves outcomes, quality of life, and survival rates in post-stroke patients. However, very few studies have identified definitive treatment for these patients; therefore, further research is required.


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About this article

Management of post-stroke neuropsychiatric disorders

Show Author's information Ahsan Ali Khan1, Lukui Chen1( ), Guilong Zhang1, Xiaoyuan Guo1, Guojian Wu1, Hong Wang1, Yang You1, Yuchun Gu2,3, Yonggui Yuan4
Department of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing 210009, China
Aston Institute of Regenerative Medicine, Aston Medical School, Aston University, Birmingham, UK
Molecular Pharmacology Laboratory, Institute of Molecular Medicine, Peking University, Beijing 100871, China
Department of Psychology, Zhongda Hospital, Southeast University, Nanjing 210009, China

Abstract

Post-stroke neuropsychiatric (NP) disorders are common and have complex etiologies. Multiple factors such as lesion location, personality characteristics, socioeconomic status, pre-stroke psychiatric history, and family support are the determining factors in most cases. Although depression and anxiety are more common, emotional incontinence and catastrophic reactions are also frequently observed. Post-stroke depression (PSD) has been associated with an increased risk of stroke recurrence. Despite its serious consequences and high prevalence, PSD remains undetected and untreated. Treatment options of NP disorders depend on severity, presentation at the time of diagnosis, and patient cooperation, and include antidepressants, mood stabilizers, exercise therapy, psychotherapy, and even revascularization. The efficient management of NP disorders improves outcomes, quality of life, and survival rates in post-stroke patients. However, very few studies have identified definitive treatment for these patients; therefore, further research is required.

Keywords: depression, anxiety, post-stroke, neuropsychiatric disorders

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Received: 09 November 2016
Revised: 12 December 2016
Accepted: 14 December 2016
Published: 01 December 2016
Issue date: December 2016

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© The authors 2016.

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