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Review Article | Open Access

Research progress on glaucoma complicated with anxiety and depression

Yan Liu1,2,3, Qing-Qing Mu1,2, Li-Qiao Ge2,3, Yuan-Yuan Zhang1,2,3, Xu Liu1, Rui-Xue Zhang1, Jun Jia1, Guo-Xin Shi1,2,3, Jia-Xing Duan1,2,3, Yuan He1,2,3( )
Department of Ophthalmology, the Second Affiliated Hospital of Xi’an Medical University, Xi’an 710038, Shaanxi Province, China
Graduate School, Xi’an Medical University, Xi’an 710021, Shaanxi Province, China
General Practice Residency Training Base, the First Affiliated Hospital of Xi’an Medical University, Xi’an 710077, Shaanxi Province, China
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Abstract

Glaucoma is a leading cause of irreversible blindness globally, with its incidence continuing to rise. Anxiety and depression are highly prevalent psychological comorbidities among patients with glaucoma. This narrative review summarizes the latest domestic and international research regarding anxiety and depression in glaucoma populations, focusing on their epidemiology, risk factors, bidirectional interactions with glaucoma, and relevant intervention strategies. This review aims to provide theoretical evidence for optimizing clinical psychosomatic comprehensive management regimens, so as to improve therapeutic outcomes and quality of life in glaucoma patients.

Keywords

glaucomaanxietydepressionprevalencerisk factorsbidirectional interactionsintervention measures

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International Journal of Ophthalmology
Volume 19 Issue 9,
September 2026
Pages 1826-1836
DOI: 10.18240/ijo.2026.09.18

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Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

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Cite this article:
Liu Y, Mu Q-Q, Ge L-Q, et al. Research progress on glaucoma complicated with anxiety and depression. International Journal of Ophthalmology, 2026, 19(9): 1826-1836. https://doi.org/10.18240/ijo.2026.09.18

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Received: 22 December 2025
Accepted: 27 February 2026
Published: 18 September 2026
© 2026 International Journal of Ophthalmology Press

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).