Research progress on acupuncture regulation of pro-inflammatory signaling pathways in the treatment of acute lung injury

Acute lung injury (ALI) is a severe and critical condition, characterized by high incidence and mortality rates, posing significant challenges to current treatment strategies. In recent years, the application of acupuncture in treating ALI has attracted widespread attention. This paper focuses on the role of acupuncture in treating ALI and systematically summarizes the mechanism by which acupuncture inhibits excessive inflammatory responses and maintains immune homeostasis through the regulation of pro-inflammatory signaling pathways such as mitogen-activated protein kinase (MAPK), nuclear factor kappa B (NF-κB), phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt), janus kinase/signal transducer and activator of transcription (JAK/STAT). Furthermore, it explores the specific role of acupuncture in reducing lung inflammation and tissue damage, providing a scientific basis and reference for further study of its anti-inflammatory mechanism and application in ALI.