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Publishing Language: Chinese | Open Access

Research progress on the “neuro-endocrine-immune” regulatory mechanism of acupuncture in the treatment of simple obesity

Wen-ting XIEYu-juan YECui MAYu-ting WEIXing-ke YAN( )
School of Acupuncture-Moxibustion and Massage, Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China
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Abstract

Acupuncture has a definite effect on the treatment of simple obesity. Acupuncture can effectively reduce the weight of patients and improve the body metabolism. Studies have shown that acupuncture in the treatment of simple obesity is closely related to the regulation of neuro-endocrine-immune function. This article reviews the neuroendocrine-immune regulatory mechanism of acupuncture in the treatment of simple obesity from the aspects of regulating key nuclei of the central nervous system, improving insulin and leptin resistance, regulating glucose and lipid metabolism, intestinal flora disorders, and regulating related immune inflammatory molecules and inflammatory signaling pathways. This review aims to provide a basis for the mechanism and application research of acupuncture in the treatment of simple obesity.

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Acupuncture Research
Pages 459-466

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Cite this article:
XIE W-t, YE Y-j, MA C, et al. Research progress on the “neuro-endocrine-immune” regulatory mechanism of acupuncture in the treatment of simple obesity. Acupuncture Research, 2025, 50(4): 459-466. https://doi.org/10.13702/j.1000-0607.20231051

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Received: 05 December 2023
Revised: 06 January 2024
Published: 03 June 2024
© The Editorial Office of Acupuncture Research

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).