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Publishing Language: Chinese

Artificial Intelligence Drives Lung Cancer Diagnosis and Treatment: Research Progress and Future Prospects

Jing BAI1Kezhong CHEN2,3,4,5Jun WANG2,3,4( )
College of Future Technology, Peking University, Beijing 100871, China
Department of Thoracic Surgery, Peking University People's Hospital, Beijing 100044, China
Thoracic Oncology Institute, Peking University People's Hospital, Beijing 100044, China
Research Unit of Intelligence Diagnosis and Treatment in Early Non-small Cell Lung Cancer, Chinese Academy of Medical Sciences(2021RU002), Beijing 100044, China
Institute of Advanced Clinical Medicine, Peking University, Beijing 100191, China
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Abstract

Lung cancer, the malignancy with the highest global mortality rate, is currently undergoing a paradigm shift from precision medicine to intelligent medicine in its diagnostic and therapeutic models. Artificial intelligence (AI), leveraging its core advantages in multimodal data fusion and high-dimensional featureextraction, has deeply permeated the entire disease continuum of lung cancer screening, diagnosis, and individualized treatment. AI demonstrates significant value in improving patient outcomes and enhancing clinical efficiency, thereby reshaping the fundamental logic and clinical practice pathways of lung cancer management. This article reviews the latest advances of AI in real-world clinical diagnosis and treatment scenarios for lung cancer, with a focus on multimodal data fusion architectures, breakthrough applications of AI-assisted lung cancer diagnosis and treatment, and the practical barriers to clinical translation. It critically analyzes core challenges including data standardization, privacy protection, and ethical compliance. Finally, it envisions the future landscape of a nationwide intelligent ecosystem for lung cancer diagnosis and treatment—driven by federated learning and empowered by data elements—providing a reference for the standardized application and innovative development of AI in precision lung cancer care.

CLC number: R734.2; TP18 Document code: A Article ID: 1674-9081(2026)03-0597-10

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Medical Journal of Peking Union Medical College Hospital
Pages 597-606

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Cite this article:
BAI J, CHEN K, WANG J. Artificial Intelligence Drives Lung Cancer Diagnosis and Treatment: Research Progress and Future Prospects. Medical Journal of Peking Union Medical College Hospital, 2026, 17(3): 597-606. https://doi.org/10.12290/xhyxzz.2026-0154

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Received: 03 February 2026
Accepted: 13 April 2026
Published: 15 May 2026
© 2026 Medical Journal of Peking Union Medical College Hospital