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Publishing Language: Chinese

Consideration of Health Economics Evidence in Clinical Practice Guidelines: Methods and Steps

Dongrui PENG1Qi ZHOU2Xufei LUO3Zijun WANG2Hui LIU2Junxian ZHAO4Jinghong HUANG5Hongyu HU1Xin XING2,8Jing WU6Shitong XIE6Xiaohui WANG1( )Yaolong CHEN1,2,4,7( )
School of Public Health, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China
Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China
Vincent V.C. Woo Chinese Medicine Clinical Research Institute, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, China
Center for Clinical Research and Evidence-Based Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China
Faculty of Social Sciences and Humanities, Mahidol University, Krung Thep Maha Nakhon 73170, Thailand
School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300000, China
Research Unit of Evidence-based Evaluation and Guidelines, Chinese Academy of Medical Sciences, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China
School of Public Health, Gansu University of Chinese Medicine, Lanzhou 730000, China
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Abstract

Health economics evidence plays an important role in linking clinical value evidence with health resource allocation decisions in the development of clinical practice guidelines. It can not only effectively balance clinical effectiveness and economic feasibility but also avoid forming "idealized" recommendations that are detached from the affordability of the healthcare system or the burden-bearing capacity of patients. To promote guideline developers to use health economics evidence more standardizedly and fully, this paper conducts an in-depth analysis of the current application status, existing challenges, access channels, and application processes of health economics evidence in current guidelines, and on this basis, puts forward considerations and suggestions for strengthening and standardizing the application of health economics evidence in China's clinical practice guidelines.

CLC number: R181.2 Document code: A Article ID: 1674-9081(2026)03-0862-09

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Medical Journal of Peking Union Medical College Hospital
Pages 862-870

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Cite this article:
PENG D, ZHOU Q, LUO X, et al. Consideration of Health Economics Evidence in Clinical Practice Guidelines: Methods and Steps. Medical Journal of Peking Union Medical College Hospital, 2026, 17(3): 862-870. https://doi.org/10.12290/xhyxzz.2026-0036

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Received: 07 January 2026
Accepted: 24 April 2026
Published: 15 May 2026
© 2026 Medical Journal of Peking Union Medical College Hospital