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Review | Publishing Language: Chinese

Research Progress on the Mechanism of Gastric Microecology in the Development of Gastric Cancer

Meng TIAN1,2,3Guobing WU1,2,3Jin YANG1,2,3Jing OUYANG1,2,3Hong CHANG1,2,3Min LIU2,3Ya ZHENG2,3Zhaofeng CHEN2,3( )
The First Clinical Medical School, Lanzhou University, Lanzhou 730000, China
Department of Gastroenterology, the First Hospital of Lanzhou University, Lanzhou 730000, China
Key Laboratory of Gastrointestinal Diseases of Gansu Province, the First Hospital of Lanzhou University, Lanzhou 730000, China
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Abstract

Microecology has been shown to be closely related to digestive diseases, and most of the research on gastric microecology has focused on Helicobacter pylori. With the development of microarray and gene detection technology, in addition to Helicobacter pylori, more and more bacteria genera have been discovered, such as Actinomyces, Firmicute and Clostridium. These bacteria genera and their abundance changes have also been proved to be closely related to the occurrence and development of gastric cancer. In this paper, the role and possible mechanism of gastric microecology in the occurrence and development of gastric cancer are reviewed, with the hope of providing reference for clinical diagnosis and treatment.

CLC number: R735.2;R-1;R37 Document code: A Article ID: 1674-9081(2023)03-0581-05

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Medical Journal of Peking Union Medical College Hospital
Pages 581-585

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Cite this article:
TIAN M, WU G, YANG J, et al. Research Progress on the Mechanism of Gastric Microecology in the Development of Gastric Cancer. Medical Journal of Peking Union Medical College Hospital, 2023, 14(3): 581-585. https://doi.org/10.12290/xhyxzz.2022-0593

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Received: 12 October 2022
Accepted: 09 February 2023
Published: 12 April 2023
© 2024 Medical Journal of Peking Union Medical College Hospital