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Publishing Language: Chinese

Gut Microbiome and Cardiovascular Health: Heart and Gut are Inextricably Linked

Xinyue ZHAO1,2Xiaomin HU2,3( )Shuyang ZHANG1,2( )
Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
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Abstract

In recent years, with the progress of multi-omics and next-generation sequencing technology, the association between gut microbiome and cardiovascular diseases has attracted great attention around the world. Gut microbiota, as a "microbial organ", directly regulates the host's health status through lipopolysaccharide, metabolites like trimethylamine oxide and short-chain fatty acids, and affects the host's immunity through bacteria and their products. "Gut-heart axis" may be a breakthrough in the prevention and treatment of cardiovascular diseases. The paper briefly discusses the relationship between gut microbiome and cardiovascular diseases, the possible ways in which gut microbes affect cardiovascular health, and the regulation of gut microbiota by various factors.

CLC number: R593;R714.252;R378 Document code: A Article ID: 1674-9081(2022)05-0725-07

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Medical Journal of Peking Union Medical College Hospital
Pages 725-731

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Cite this article:
ZHAO X, HU X, ZHANG S. Gut Microbiome and Cardiovascular Health: Heart and Gut are Inextricably Linked. Medical Journal of Peking Union Medical College Hospital, 2022, 13(5): 725-731. https://doi.org/10.12290/xhyxzz.2022-0444

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Received: 12 August 2022
Accepted: 24 August 2022
Published: 07 September 2022
© 2024 Medical Journal of Peking Union Medical College Hospital