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Review | Publishing Language: Chinese

Research Progress on the Relationship Between Helicobacter Pylori Associated Chronic Atrophic Gastritis and Gastric Cancer

Guobing WU1,2,3, Xiaolong CHENG1,2,3, Xiao YU1,2,3, Aibin ZHANG1,2,3, Min LIU2,3, Zhaofeng CHEN2,3( )
The First Clinical Medical School, Lanzhou University, Lanzhou 730000, China
Department of Gastroenterology, the First Hospital of Lanzhou University, Lanzhou 730000, China
Key Laboratory of Gastrointestinal Diseases of Gansu Province, the First Hospital of Lanzhou University, Lanzhou 730000, China
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Abstract

Helicobacter pylori(HP) associated chronic atrophic gastritis (CAG) is known to be a precancerous lesion of gastric cancer, and can act on gastric carcinogenesis through a variety of factors, but the specific mechanism of action is not yet clear. In this paper, we review the research progress of the mechanism of HP associated CAG in the development of gastric cancer to provide reference for clinical medical staff.

Keywords

Helicobacter pylorichronic atrophic gastritisgastric cancer
CLC number: R735.2;R516;R573 Document code: A Article ID: 1674-9081(2023)02-0339-07

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Medical Journal of Peking Union Medical College Hospital
Volume 14 Issue 2,
March 2023
Pages 339-345
DOI: 10.12290/xhyxzz.2022-0374

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WU G, CHENG X, YU X, et al. Research Progress on the Relationship Between Helicobacter Pylori Associated Chronic Atrophic Gastritis and Gastric Cancer. Medical Journal of Peking Union Medical College Hospital, 2023, 14(2): 339-345. https://doi.org/10.12290/xhyxzz.2022-0374

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Received: 17 May 2022
Accepted: 22 July 2022
Published: 29 July 2022
© 2024 Medical Journal of Peking Union Medical College Hospital