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Publishing Language: Chinese

Primary Epithelial-myoepithelial Carcinoma of Thymus: First Case Report of the World and Literature Review

Xiang WANG1, Yajuan SHAO1, Guibin SUN2, Na ZHOU1, Hongnan ZHEN3, Jie CHEN4, Lin ZHAO1( ), Chunmei BAI1
Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Department of Medical Oncology, Beijing Puren Hospital, Beijing 100062, China
Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
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Abstract

Objective

To analyze the clinical, imaging and pathological features of patients with epithelial-myoepithelial carcinoma(EMC).

Methods

The data of a patient with primary EMC of the thymus in Peking Union Medical College Hospital was retrospectively analyzed, and the relevant literature was reviewed.

Results

The patient was a middle-aged male diagnosed with primary EMC of the thymus, and he was the first case currently reported at home and abroad. Even though the patient received comprehensive treatments including surgery, chemotherapy, radiotherapy and molecular targeted therapy, he still experienced disease progression, with a survival time of 22 months after surgery.

Conclusions

Primary EMC of the thymus is extremely rare and has atypical clinical manifestations. The diagnosis mainly depends on histopathological examination. Surgery is currently the major treatment and multidisciplinary treatment is very important to prolong the survival time of EMC patients.

Keywords

epithelial-myoepithelial carcinomaprimary disease of thymusrare disease
CLC number: R736.3 Document code: A Article ID: 1674-9081(2022)05-0864-07

References

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Medical Journal of Peking Union Medical College Hospital
Volume 13 Issue 5,
September 2022
Pages 864-870
DOI: 10.12290/xhyxzz.2022-0318

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Cite this article:
WANG X, SHAO Y, SUN G, et al. Primary Epithelial-myoepithelial Carcinoma of Thymus: First Case Report of the World and Literature Review. Medical Journal of Peking Union Medical College Hospital, 2022, 13(5): 864-870. https://doi.org/10.12290/xhyxzz.2022-0318

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Received: 09 June 2022
Accepted: 11 July 2022
Published: 27 July 2022
© 2024 Medical Journal of Peking Union Medical College Hospital