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Clinical Study | Publishing Language: Chinese | Open Access

Neural network analysis of the correlation between malnutrition-induced stomatitis and vitamin B12 and folic acid

Ruowei LI1Ke LIU2Miaomiao ZHANG1Ruiqi XIE1Ning DUAN1Wenmei WANG1Xiang WANG1( )
Department of Oral Medicine, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China
Nanjing University of Posts and Telecommunications, Nanjing 210023, China
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Abstract

Objective

A model was built by neural network analysis to study the relationship between different degrees of vitamin B12 and folic acid deficiency and malnutrition-induced stomatitis.

Methods

Data from 30 healthy volunteers and 30 patients with malnutrition-induced stomatitis were collected. The distribution of lesions, the number of affected sites and clinical manifestations were recorded, and the severity was scored. The levels of vitamin B12 and folic acid in the peripheral blood of the two groups were simultaneously measured. The SPSS software was used to analyze the correlation between vitamin B12 and folic acid levels in the peripheral blood of patients with malnutrition-induced stomatitis and healthy volunteers, and the MATLAB software package was used to analyze the data via a neural network.

Results

The levels of vitamin B12 and folic acid significantly correlated with the grade of malnutrition-induced stomatitis. Simultaneous B12 and folic acid deficiency linearly correlated with the occurrence and severity of malnutrition-induced stomatitis. Based on this correlation, a thermogram model of malnutrition-induced stomatitis was constructed.

Conclusion

Malnutrition-induced stomatitis is closely related to vitamin B12 and folic acid deficiency. Their synergistic effect may promote the occurrence and development of malnutrition-induced stomatitis. The construction of the malnutrition-induced stomatitis model aids the targeted etiological treatment of patients with moderate and severe deficiency to prevent malnutrition-induced stomatitis.

CLC number: R78 Document code: A Article ID: 2096-1456(2022)12-0858-06

References

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Journal of Prevention and Treatment for Stomatological Diseases
Pages 858-863

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Cite this article:
LI R, LIU K, ZHANG M, et al. Neural network analysis of the correlation between malnutrition-induced stomatitis and vitamin B12 and folic acid. Journal of Prevention and Treatment for Stomatological Diseases, 2022, 30(12): 858-863. https://doi.org/10.12016/j.issn.2096-1456.2022.12.004

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Received: 13 April 2022
Revised: 06 June 2022
Published: 20 December 2022
© 2022 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases