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Expert Forum | Publishing Language: Chinese | Open Access

Progress in storage and clinical application of dental stem cells

Qingsong YE1,2,3( ), Xiaoyan WANG2,3
School of Dentistry, University of Queensland, Brisbane 4006, Australia
Institute of Stem Cells and Tissue Engineering, School of Stomatology, Wenzhou Medical University, Wenzhou 325035, China
UQ-WMU Joint Group for Regenerative Dentistry, Faculty of Health and Behavior Science, University of Queensland, Brisbane 4006, Australia
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Abstract

Derived from the neural crest, dental stem cells (DSCs) are a population of cells with the characteristics of mesenchymal stem-ness, which under certain appropriate conditions can differentiate into multiple cells such as osteocytes, chondrocytes, hepatocyte and neuronal-like cells. DSCs are consist of odontogenic stem cells mainly include dental pulp stem cells, periodontal ligament stem cells, stem cells from deciduous teeth, stem cells from apical papilla, as well as dental follicle progenitor cells. DSCs have been widely used in the field of regenerative medicine research and preclinical research, including nervous system diseases, oral diseases, immune diseases, heart and lung diseases, etc. This review will focus on the storage of DSCs and current translational and clinical studies regarding DSCs in tissue regeneration.

Keywords

OdontogenicStem cellsRegenerative medicineTranslational researchClinical trialsStem cells BankingTissue engineering
CLC number: R78 Document code: A Article ID: 2096-1456(2018)01-0015-11

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Journal of Prevention and Treatment for Stomatological Diseases
Volume 26 Issue 1,
January 2018
Pages 15-25
DOI: 10.12016/j.issn.2096-1456.2018.01.004

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YE Q, WANG X. Progress in storage and clinical application of dental stem cells. Journal of Prevention and Treatment for Stomatological Diseases, 2018, 26(1): 15-25. https://doi.org/10.12016/j.issn.2096-1456.2018.01.004

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Received: 31 August 2017
Revised: 03 November 2017
Published: 20 January 2018
© 2018 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases

This article is licensed under a Creative Commons Attribution 4.0 International License.