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Review Article | Publishing Language: Chinese | Open Access

Advances in research on the prevention and treatment of dental erosion by MMPs inhibitors

Nengwu JIANG1,2, Hao YU1,2( )
Department of Prosthodontics, School and Hospital of Stomatology, Fujian Medical University, Fuzhou 350002, China
Fujian Biological Materials Engineering and Technology Center of Stomatology, Fuzhou 350002, China
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Abstract

High prevalence of dental erosion has been reported in recent years. The prevention and treatment of dental erosion has therefore attracted lots of attention in dentistry. Matrix metalloproteinases (MMPs) is a type of proteolytic enzyme containing Zn2+ and Ca2+, which can degrade organic matrix in advanced dental erosion. MMPs inhibitors were reported to have the potential to prevent the organic matrix of dentin from degradation, which might provide protective capacity against dental erosion. The present article reviews the mechanism and potential application of MMPs inhibitors in the prevention and treatment of dental erosion.

Keywords

Dental erosionDentinPreventionTherapyMMPsMMPs inhibitors
CLC number: R781.2 Document code: A Article ID: 2096-1456(2017)12-0810-04

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Journal of Prevention and Treatment for Stomatological Diseases
Volume 25 Issue 12,
December 2017
Pages 810-813
DOI: 10.12016/j.issn.2096-1456.2017.12.013

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JIANG N, YU H. Advances in research on the prevention and treatment of dental erosion by MMPs inhibitors. Journal of Prevention and Treatment for Stomatological Diseases, 2017, 25(12): 810-813. https://doi.org/10.12016/j.issn.2096-1456.2017.12.013

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Received: 14 March 2017
Revised: 07 April 2017
Published: 20 December 2017
© 2017 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases

This article is licensed under a Creative Commons Attribution 4.0 International License.