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Basic Study | Publishing Language: Chinese | Open Access

The analysis of expression of HAase in oral squamous cell carcinoma

Jingxu WANG1( ), Guiqing LIAO2
Department of Stomatology, Guanzhou Medical University, Guangzhou 510182, China
Department of Oral and Maxillofaial Surgery, Guanghua Shool of Stomatology, Sun Yet-sen University, Guangzhou 510182, China
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Abstract

Objective

To evaluate the expression of HAase in Oral Squamous Cell Caricinoma (OSCC).

Methods

The distribution and expression of HAase in 21 patients with OSCC and their resecetions with tumor-free margins were examined by immunohistochemistry method.

Results

HAase were mainly immunostained in tumor tissue. The expression of HAase in oral cancer with nodal metastasis and low pathological grades were higher than that with no nodal metastasis and high pathological grades (P < 0.05), whereas no difference between the TNM stages (P > 0. 05).

Conclusion

The HAase levels were high in oral squamous cell carcinoma tissues, and rising in patients with lymph node metastasis and poorly differentiated.

Keywords

OralSquamous cell carcinomaHyaluronidaseTumorImmunohistochemistry
CLC number: R739.8 Document code: A Article ID: 2096-1456(2017)10-0638-03

References

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Journal of Prevention and Treatment for Stomatological Diseases
Volume 25 Issue 10,
October 2017
Pages 638-640
DOI: 10.12016/j.issn.2096-1456.2017.10.005

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WANG J, LIAO G. The analysis of expression of HAase in oral squamous cell carcinoma. Journal of Prevention and Treatment for Stomatological Diseases, 2017, 25(10): 638-640. https://doi.org/10.12016/j.issn.2096-1456.2017.10.005

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Received: 31 May 2017
Revised: 04 August 2017
Published: 20 October 2017
© 2017 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases

This article is licensed under a Creative Commons Attribution 4.0 International License.