Effects of blood glucose control in type 2 diabetes mellitus on implant stability and blood inflammatory markers

To investigate the effects of blood glucose levels in type 2 diabetes mellitus (T2DM) on implant stability and blood inflammatory markers.

35 patients with T2DM were selected as the observation group, and 30 healthy individuals were included in the control group. All the patients received implant surgery. The level of the blood glucose control, the inflammatory indexes of blood, and the implant stability were recorded and analyzed.

There was no significant difference in the inflammation indexes between the 2 groups before surgery (P＞0.05). The numbers of white blood cells, grain cells and lymphocyte in the observation group were significantly higher than those in control group after implantation (P＜0.01). The immediate implant torque values were(32.65 ± 3.48) N·cm and(28.75 ± 3.64) N·cm in control group and observation group respectively, and the average torque value of the control group was significantly higher than that of the observation group (t = 2.945, P = 0.016). The postoperative implant stability quotient(ISQ) decreased at first, and then increased gradually. There was no significant difference in ISQ between the 2 groups at the early stage (P＞0.05), what’s more, when ISQ decreased to the lowest level after 2 weeks, there was no significant difference either (P＞0.05). Individuals with worse blood glucose level control were observed to have a longer time to recover the ISQ level (P＜0.05).

Blood glucose level may have some effects on the inflammatory reaction and implant stability in the patients with T2DM.