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Prevention and Treatment Practice | Publishing Language: Chinese | Open Access

Comparative study on the clinical effect of minocycline hydrochloride ointment and lodine glycerin as adjuvant therapy for pericoronitis with parulis

Guang-hua GE1( ), Jin-fang LI, Xiao-ping JIANG, Qiong WU
Department of Stomatology, Hospital of Guangdong University of Technology, Guangzhou 510006, China
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Abstract

Objective

To compare the clinical effects of minocycline hydrochloride ointment (Periocline) and lodine glycerin as adjuvant therapy for pericoronitis with parulis.

Methods

164 college students suffering from pericoronitis with parulis were divided into 2 groups randomly: observation group (82 cases) and control group (82 cases). All cases were treated with incision and drainage of the parulis, and then pericoronal rinsing. What’s more, tinidazole and cefradine plus compound borax gargle mouthwash were given to them. 2% Periocline was filled into the periodontal pocket for the observation group (q3d) while 1% lodine glycerin was filled into the periodontal pocket for the control group (qd). Clinical effects of the two groups were observed and compared 3 days later.

Results

The effective rate of observation group (93.9%) was higher than that of control group (78.0%) with statistically significance (χ2= 8.546, P =0.003). No drug adverse reaction occured.

Conclusion

It shows good effects when Periocline is applied as an adjuvant therapy for pericoronitis with parulis.

Keywords

The third molarPericoronitisMinocyclineLodine glycerinRelease drug
CLC number: R782.3 Document code: A Article ID: 2096-1456(2016)06-366-04

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Journal of Prevention and Treatment for Stomatological Diseases
Volume 24 Issue 6,
June 2016
Pages 366-369
DOI: 10.12016/j.issn.2096-1456.2016.06.011

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GE G-h, LI J-f, JIANG X-p, et al. Comparative study on the clinical effect of minocycline hydrochloride ointment and lodine glycerin as adjuvant therapy for pericoronitis with parulis. Journal of Prevention and Treatment for Stomatological Diseases, 2016, 24(6): 366-369. https://doi.org/10.12016/j.issn.2096-1456.2016.06.011

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Received: 20 December 2015
Revised: 06 January 2016
Published: 20 June 2016
© 2016 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases

This article is licensed under a Creative Commons Attribution 4.0 International License.