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Expert Forum | Publishing Language: Chinese | Open Access

Research progress on the invasion and metastasis of tongue squamous cell carcinoma

Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
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Abstract

Tongue squamous cell carcinoma (TSCC) is the most common cancer of head and neck malignancies. Despite advances in therapeutic management, the prognosis for TSCC patients has remained poor. Local or regional relapse and cervical lymph node metastasis are clinical challenges. This review has introduced the research progress on cancer invasion and metastasis related genes, micro RNAs, EMT and cancer stem cells behavior and so on. With the further study on the mechanisms of invasion and metastasis of TSCC, the difficulties might be overcome.

Keywords

TongueSquamous cell carcinomaInvasionMetastasisTumor stem cells
CLC number: R739.8 Document code: A Article ID: 2096-1456(2016)05-261-06

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Journal of Prevention and Treatment for Stomatological Diseases
Volume 24 Issue 5,
May 2016
Pages 261-266
DOI: 10.12016/j.issn.2096-1456.2016.05.001

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WANG A-x. Research progress on the invasion and metastasis of tongue squamous cell carcinoma. Journal of Prevention and Treatment for Stomatological Diseases, 2016, 24(5): 261-266. https://doi.org/10.12016/j.issn.2096-1456.2016.05.001

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Received: 07 January 2016
Revised: 18 January 2016
Published: 20 May 2016
© 2016 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases

This article is licensed under a Creative Commons Attribution 4.0 International License.