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Clinical Research | Publishing Language: Chinese | Open Access

Effect of intradialytic exercise on dialysis adequacy and physical function in elderly maintenance dialysis patients

Jiajie Wen1, Xiaohui Lai1( ), Jiandong Chen2, Kuihuan Xie1
Blood Purification Centre, The Tenth Affiliated Hospital of Southern Medical University, Dongguan People′s Hospital, Dongguan 523000, Guangdong Province, China
Department of Rehabilitation, The Tenth Affiliated Hospital of Southern Medical University, Dongguan People′s Hospital, Dongguan 523000, Guangdong Province, China
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Abstract

Objective

To investigate the effect of intradialytic exercise (IDE) on dialysis adequacy and physical function in elderly patients undergoing maintenance dialysis (MHD).

Methods

A total of 168 elderly MHD patients admitted to the Tenth Affiliated Hospital of Southern Medical University between January 2022 and June 2024 were enrolled. These patients were randomly divided into a trial group and a control group, with 84 patients in each group. The control group received routine conventional dialysis intervention, while the trial group additionally underwent IDE. The withdrawal rate and reasons for withdrawal from IDE in the trial group were statistically described. After excluding the withdrawal patients in the trial group, the differences in dialysis adequacy, sleep quality, fatigue status, and physical fitness were compared before and after intervention and between two groups. SPSS statistics 27.0 was used for statistical analysis. Intergroup comparisons were performed using t test or Chi-square test depending on data type.

Results

Among the 84 elderly MHD patients in the trial group, 7 were withdrawn, with a withdrawal rate of 8.33%. After intervention, the trial group exhibited significantly higher single-pool urea clearance (Kt/V), longer distance in 6 min walking test (6MWT), and faster step speed and maximum step speed, and obviously lower scores of Pittsburgh sleep quality index (PSQI) and Piper fatigue scale (PFS) than the pre-intervention levels (P<0.05). After intervention, the Kt/V, 6MWT, normal step speed and maximum step speed were obviously higher while the scores of PSQI and PFS were significantly lower in the trial group than in the control group (P<0.05).

Conclusion

IDE can effectively improve dialysis adequacy, sleep quality and physical fitness, and alleviate fatigue in elderly MHD patients.

CLC number: R459.5;R592 Document code: A

References

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Chinese Journal of Multiple Organ Diseases in the Elderly
Pages 620-624

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Cite this article:
Wen J, Lai X, Chen J, et al. Effect of intradialytic exercise on dialysis adequacy and physical function in elderly maintenance dialysis patients. Chinese Journal of Multiple Organ Diseases in the Elderly, 2026, 25(8): 620-624. https://doi.org/10.11915/j.issn.1671-5403.2026.08.123

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Received: 01 August 2025
Accepted: 23 September 2025
Published: 28 August 2026
© 2026 Chinese Journal of Multiple Organ Diseases in the Elderly

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).