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Journal of Geriatric Cardiology 2022, 19(4): 292-300 https://doi.org/10.11909/j.issn.1671-5411.2022.04.006
Research Article | Open Access | Issue | Published: 28 April 2022

Trends and sex differences in atrial fibrillation hospitalization and catheter ablation at tertiary hospitals in China from 2013 to 2016

Show Author's Information Kang LI1,*,  Fang-Fang FAN1,*,  Peng-Fei SUN1,  Jie JIANG1,  Jing ZHOU1,  Ying SHI2,  Hai-Bo WANG3,  Jian-Ping LI1,  Yan ZHANG1( ),  Yong HUO1( )
Department of Cardiology, Peking University First Hospital, Beijing, China
Scientific Project Department, China Standard Medical Information Research Centre, Shenzhen, China
Clinical Trial Unit, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China

*The authors contributed equally to this manuscript

Cite this article:
LI K, FAN F-F, SUN P-F, et al. Trends and sex differences in atrial fibrillation hospitalization and catheter ablation at tertiary hospitals in China from 2013 to 2016. Journal of Geriatric Cardiology, 2022, 19(4): 292-300. https://doi.org/10.11909/j.issn.1671-5411.2022.04.006
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Abstract Full text About this article
BACKGROUND

Catheter ablation for atrial fibrillation (AF) is commonly performed worldwide. However, the clinical characteristics of hospitalized patients with AF and national trends in catheter ablation at tertiary hospitals in China remain unreported.

METHODS

This study used the Chinese national database (Hospital Quality Monitoring System) from 2013 to 2016, which is a mandatory database that collects the front page of patients’ medical records for hospital accreditation, to describe the clinical characteristics of patients with AF as an overall cohort and as subgroups divided by catheter ablation and sex.

RESULTS

Of 597,919 AF patients first admitted, 57,983 patients underwent catheter ablation [56,384 cases (97.2%) of radiofrequency ablation and 1599 cases (2.8%) of cryoablation] at 746 tertiary hospitals. Nearly 10% of patients hospitalized with AF at tertiary hospitals in China underwent catheter ablation, and the percentage of patients undergoing catheter ablation was on the rise between 2013 and 2016, and the number of cases increased by 2.5 times. Compared with AF patients who did not undergo catheter ablation, those who did were younger, more frequently male, and had fewer baseline comorbidities. Although the overall CHA2DS2VASc score revealed over half of the patients were high-risk, patients who underwent catheter ablation were mostly low-risk (71.2% of males and 59.1% of females). Considering in-hospital adverse events, the overall pericardial tamponade and all-cause death incidences were 0.2% (0.6% in the ablation group) and 1.2% (0.1% in the ablation group), respectively; both of which were higher in females than males.

CONCLUSIONS

In this study, AF patients who underwent catheter ablation were relatively young, had a low thrombosis risk, and had few comorbidities and adverse events. Females were older and experienced more complications than males.


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Abstract
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About this article

Trends and sex differences in atrial fibrillation hospitalization and catheter ablation at tertiary hospitals in China from 2013 to 2016

Show Author's information Kang LI1,*, Fang-Fang FAN1,*, Peng-Fei SUN1, Jie JIANG1, Jing ZHOU1, Ying SHI2, Hai-Bo WANG3, Jian-Ping LI1, Yan ZHANG1( ), Yong HUO1( )
Department of Cardiology, Peking University First Hospital, Beijing, China
Scientific Project Department, China Standard Medical Information Research Centre, Shenzhen, China
Clinical Trial Unit, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China

*The authors contributed equally to this manuscript

Abstract

BACKGROUND

Catheter ablation for atrial fibrillation (AF) is commonly performed worldwide. However, the clinical characteristics of hospitalized patients with AF and national trends in catheter ablation at tertiary hospitals in China remain unreported.

METHODS

This study used the Chinese national database (Hospital Quality Monitoring System) from 2013 to 2016, which is a mandatory database that collects the front page of patients’ medical records for hospital accreditation, to describe the clinical characteristics of patients with AF as an overall cohort and as subgroups divided by catheter ablation and sex.

RESULTS

Of 597,919 AF patients first admitted, 57,983 patients underwent catheter ablation [56,384 cases (97.2%) of radiofrequency ablation and 1599 cases (2.8%) of cryoablation] at 746 tertiary hospitals. Nearly 10% of patients hospitalized with AF at tertiary hospitals in China underwent catheter ablation, and the percentage of patients undergoing catheter ablation was on the rise between 2013 and 2016, and the number of cases increased by 2.5 times. Compared with AF patients who did not undergo catheter ablation, those who did were younger, more frequently male, and had fewer baseline comorbidities. Although the overall CHA2DS2VASc score revealed over half of the patients were high-risk, patients who underwent catheter ablation were mostly low-risk (71.2% of males and 59.1% of females). Considering in-hospital adverse events, the overall pericardial tamponade and all-cause death incidences were 0.2% (0.6% in the ablation group) and 1.2% (0.1% in the ablation group), respectively; both of which were higher in females than males.

CONCLUSIONS

In this study, AF patients who underwent catheter ablation were relatively young, had a low thrombosis risk, and had few comorbidities and adverse events. Females were older and experienced more complications than males.

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Published: 28 April 2022
Issue date: April 2022

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© 2022 JGC All rights reserved

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ACKNOWLEDGMENTS

This study was supported by the China-WHO Biennial Collaborative Projects 2016–2017 (No.2016/648722–0). All authors had no conflicts of interest to disclose. The authors thank all China Standard Medical Information Research Centre members for their help and support throughout the study.

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