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Review | Publishing Language: Chinese | Open Access

Research progress and application prospects of postbiotics derived from Saccharomyces boulardii

Xuemei YUAN1,2Hu WANG1,2Haili YU1,2Xiaowen LIU3Yan ZHANG1,2
National Key Laboratory of Agricultural Microbiology, Yichang 443000, China
Hubei Provincial Key Laboratory of Yeast Function, Yichang 443000, China
Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, School of Basic Medical Sciences, China Three Gorges University, Yichang 443002, China
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Abstract

Saccharomyces boulardii is a non-pathogenic yeast and one of the most well-known probiotic yeast. Since its discovery, it has been widely used as a health supplement and medical products globally, being a yeast with various biological activities. Clinical studies have shown that S. boulardii can improve intestinal diseases, irritable bowel syndrome, and Helicobacter pylori infections, and it possessed anti-cancer, immunomodulatory, antibacterial, antiviral, and antioxidant functions. In recent years, with the development of microbial ecology and nutrition, the research on S. boulardii as a postbiotics has attracted widespread attention in the scientific community. However, the research on postbiotics derived from S. boulardii is still in its infancy. Based on this point of view, the biological characteristics of S. boulardii and its action mechanism in the body, as well as the application prospect of postbiotics derived from S. boulardii in food and medicine were reviewed, in order to provide a theoretical basis for the wide application of postbiotics derived from S. boulardii.

CLC number: TQ926.4 Article ID: 0254-5071(2025)08-0015-07

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China Brewing
Pages 15-21

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Cite this article:
YUAN X, WANG H, YU H, et al. Research progress and application prospects of postbiotics derived from Saccharomyces boulardii. China Brewing, 2025, 44(8): 15-21. https://doi.org/10.11882/j.issn.0254-5071.2025.08.003

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Received: 14 August 2024
Revised: 24 December 2024
Published: 25 August 2025
© Beijing Academy of Food Sciences 2025.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).