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Review | Open Access

The role of artificial intelligence in burn assessment, complication diagnosis, and outcome prediction: a narrative review

Punit Bhattachan1,2,3,Zachary Ricciuti2,3,4,Fadi Khalaf2,3,5Marc G Jeschke1,2,3,4,5 ( )
Department of Surgery, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada
Centre for Burn Research, Hamilton Health Sciences, 20 Copeland Ave, Hamilton, ON, L8L 2X2, Canada
David Braley Research Institute, Hamilton Health Sciences, 20 Copeland Ave, Hamilton, ON, L8L 2X2, Canada
Department of Medical Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada
Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada

Punit Bhattachan and Zachary Ricciuti contributed equally to this work.

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Abstract

Burn injury remains a major global health challenge, causing an estimated 180000 deaths annually. The marked heterogeneity in burn severity, complications, and outcomes highlights the need for more objective and efficient evaluation strategies. Artificial intelligence (AI) has emerged as a promising approach to support clinical decision-making and improve patient care in this field. In this narrative review, we summarize the growing applications of AI in burn care, including the assessment of burn depth and total body surface area, monitoring of wound healing, prediction of postburn complications, and estimation of clinical outcomes. AI-based models have demonstrated strong performance in automating wound assessment, optimizing fluid resuscitation, and predicting complications such as sepsis, inhalation injury, and acute kidney injury. Furthermore, AI-driven prediction of mortality risk and hospital length of stay has shown potential to inform early interventions and improve resource allocation. Despite encouraging progress, most studies to date rely on small, single-center datasets and limited model validation, underscoring the need for larger, multi-institutional efforts, and standardized data sharing. Integrating AI into burn management holds great promise for enhancing diagnostic precision, forecasting outcomes, and personalizing treatment strategies. As these technologies advance, clinician familiarity and collaboration with AI tools will be critical to fully realize their potential in transforming burn care.

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Burns & Trauma
Article number: tkaf071

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Cite this article:
Bhattachan P, Ricciuti Z, Khalaf F, et al. The role of artificial intelligence in burn assessment, complication diagnosis, and outcome prediction: a narrative review. Burns & Trauma, 2026, 14(1): tkaf071. https://doi.org/10.1093/burnst/tkaf071

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Received: 24 March 2025
Revised: 27 October 2025
Accepted: 27 October 2025
Published: 30 October 2025
© The Author(s) 2025. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.