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Review | Open Access

Biomimetic nano dressing in wound healing: design strategies and application

Menglei Wang‡, Haiqing Li‡, Yawen Luo, Jiawen Chen, Ziyi Tang, Yu Wei, Qianwen Yang, Wantong Xiao, Wanchun You, Meixin Feng, Jing Shen, Li Li ( )
Department of Dermatology, Nanfang Hospital, Southern Medical University, Jingxi Street, Baiyun District, Guangzhou 510515, Guangdong, China

‡These authors contributed equally to this work.

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Highlights

• This review highlights that biomimetic nano dressings have great potential in wound management.

• Biomimetic nano dressings have superior biological activity, biocompatibility, and stimuli-responsive properties compared with traditional wound dressings.

• Biomimetic nano dressings offer novel solutions for wound repair by mimicking the structure and function of natural extracellular matrix.

Abstract

Biomimetic nano dressings have superior biological activity, biocompatibility, and stimuli-responsive properties compared with traditional wound dressings due to their biomimetic design integration and show great potential in wound management. This review summarizes the materials and techniques used to prepare current biomimetic nano dressings, focusing on biomimetic design strategies. Moreover, we explore the application of biomimetic nano dressings in treating wounds associated with infections, burns, diabetes, and postoperative skin cancer. This review provides new perspectives on the design of biomimetic nano dressings and highlights future research directions to further advance innovative wound treatment strategies.

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Keywords

Biomimetic nano dressingsBurnsDesign strategiesDiabetic woundsExtracellular matrixHealingWound

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Burns & Trauma
Volume 13 Issue 8,
August 2025
Article number: tkaf038
DOI: 10.1093/burnst/tkaf038

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Cite this article:
Wang M, Li H, Luo Y, et al. Biomimetic nano dressing in wound healing: design strategies and application. Burns & Trauma, 2025, 13(8): tkaf038. https://doi.org/10.1093/burnst/tkaf038

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Received: 24 November 2024
Revised: 16 May 2025
Accepted: 29 May 2025
Published: 10 June 2025
© The Author(s) 2025. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site-for further information please contact journals.permissions@oup.com.