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Guideline | Open Access

Consensus on the diagnosis and treatment of adult necrotizing fasciitis (2025 edition)

Institute of Burn Research, The First Affiliated Hospital of Army Medical University, (the Third Military Medical University) Gaotanyan Street, Chongqing 400038, China
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Highlights

• Currently, no standardized protocol exists for diagnosing and treating necrotizing fasciitis. This consensus, formulated through multidisciplinary expert discussions, integrates recent guidelines, literature, and clinical practice experiences, adhering to evidence-based medicine principles.

• This document presents recommendations for standardizing the diagnosis and treatment of necrotizing fasciitis. These findings serve as a basis for further refinement of diagnostic and therapeutic strategies for this condition.

Abstract

Necrotizing fasciitis (NF) is a disease characterized by severe infection of the skin and its underlying soft tissues as the initial symptom. NF is known for its difficulty in early diagnosis and rapid progression. If not treated promptly, NF can quickly evolve into systemic infection, sepsis, and multiple organ failure, and it may even lead to patient death. Currently, many controversies and challenges remain in clinical practice for the diagnosis and treatment of NF. To promote the standardization of NF diagnosis and treatment, Chinese Burn Association, Editorial Board of the Chinese Journal of Burns and Wounds, and Burn Medicine Branch of China International Exchange and Promotion Association for Medical and Health Care, based on the latest relevant guidelines, literature, and clinical practice experience and in accordance with the principles of evidence-based medicine, have jointly developed the Consensus on the Diagnosis and Treatment of Adult Necrotizing Fasciitis (2025 Edition) through repeated discussion and voting. This consensus aims to provide scientific and standardized guidance for clinical diagnosis and treatment.

Keywords

Necrotizing fasciitisMultidisciplinaryConsensus

References

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Burns & Trauma
Volume 13 Issue 6,
June 2025
Article number: tkaf031
DOI: 10.1093/burnst/tkaf031

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Cite this article:
Zhou L, Li H, Luo G. Consensus on the diagnosis and treatment of adult necrotizing fasciitis (2025 edition). Burns & Trauma, 2025, 13(6): tkaf031. https://doi.org/10.1093/burnst/tkaf031

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Received: 10 April 2025
Revised: 06 May 2025
Accepted: 08 May 2025
Published: 10 October 2026
© The Author(s) 2025. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.