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Review | Open Access

Modified constraint-induced movement therapy for lower extremity intervention on patients with stroke: A Scoping Review

Liping Zhoua,b, Huaide Chub, Manting Caoa, Nur Arzuar Abdul Rahimc, Hazwani Ahmad Yusofa( ), Ying Houd( )
Department of Community Health, Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Kepala Batas, Pulau Pinang, Malaysia
The Fourth People's Hospital of Kunshan, Lujia Town, Kunshan City, Jiangsu Province 215331, China
Department of Clinical Medicine, Advanced Medical and Dental Institute, University Sains Malaysia, 13200 Kepala Batas, Pulau Pinang, Malaysia
The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou 215008, China

Peer review under the responsibility of Editorial Board of Sports Medicine and Health Science

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Abstract

Background

Stroke is the main cause of long-term disability, burdening people and healthcare systems. In stroke patients, modified Constraint-Induced Movement Therapy (mCIMT) may improve lower extremity function. Protocol variability complicates efficacy evaluation.

Objectives

For stroke patients' lower extremity rehabilitation, examine mCIMT safety and effectiveness and identify important protocol components for motor recovery augmentation.

Methods

An extensive PubMed, Web of Science, Scopus, and PEDro search found clinical studies on mCIMT for lower extremity mobility impairments in adult stroke patients published between January 1, 2000, and November 30, 2023. Constraints, doses, transfer packages, and outcome measures analyzed heterogeneity and study classifications appraised quality.

Results

36 trials with 931 stroke victims were examined. Heterogeneity prevented clear results on the best mCIMT methods. Studies show that mCIMT improves motor function, functional mobility, balance, lower limb strength, weight-bearing, and walking ability with minor side effects. Physical restraint devices may be unsafe and painful. For safety, behavioral limitations are advised. Instead of training length, task repetitions are a better indication of training intensity and can decrease training time. Transfer packages help transfer training gains to daily activities and preserve long-term effects, as shown by better real-world walking habits and functional mobility during follow-up.

Conclusions

mCIMT is safe and effective for stroke lower extremity rehabilitation. Behavioral limitations, a specified dose of task repetitions, and patient-specific transfer packages are recommended for mCIMT. Standardizing methods and finding appropriate component combinations to overcome heterogeneity and improve clinical applicability and patient outcomes require further study.

References

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Sports Medicine and Health Science
Pages 291-301

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Cite this article:
Zhou L, Chu H, Cao M, et al. Modified constraint-induced movement therapy for lower extremity intervention on patients with stroke: A Scoping Review. Sports Medicine and Health Science, 2026, 8(3): 291-301. https://doi.org/10.1016/j.smhs.2025.06.001

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Received: 15 November 2024
Revised: 18 February 2025
Accepted: 03 June 2025
Published: 25 June 2025
© 2025 Chengdu Sport University.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).