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Opinion Paper | Open Access

Use of traditional Chinese medicine in the treatment of immune-related adverse events of cancer immunotherapy

Li Houa,1, Liya Jub,1, Jing Wanga, Tian Zhouc, Yang Shena, Jiaqi Chic, Jean-Pierre Armandd, Anlong Xue, Kaiwen Huc( )
Department of Hematology and Oncology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
HLA et Medicine, Batiment Bazin, Saint-Louis Hospital, Paris 75010, France
Department of Oncology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China
Gustave Roussy, Villejuif 94805, France
School of Life Sciences, Beijing University of Chinese Medicine, Beijing 102488, China

1 These authors contributed equally to this article.

Peer review under responsibility of Beijing University of Chinese Medicine.

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Abstract

Immune checkpoint inhibitors (ICPI) have shown considerable promise in the treatment of tumors. However, immune-related adverse events (irAEs) caused by ICPI have been reported in nearly every organ system. Whilst this represents a new challenge in the field of cancer treatment, traditional Chinese medicine (TCM) provides benefits in the treatment of irAEs. This article reviews the studies of the treatment of immune-related gastrointestinal diseases and dermatosis with TCM and introduces the collaborative efforts between China and France in the implementation of TCM for the treatment of irAEs.

Keywords

Immune-related adverse eventsTraditional Chinese medicineCancer immunotherapyImmune checkpoint inhibitors

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Journal of Traditional Chinese Medical Sciences
Volume 5 Issue 4,
October 2018
Pages 323-327
DOI: 10.1016/j.jtcms.2018.12.002

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Cite this article:
Hou L, Ju L, Wang J, et al. Use of traditional Chinese medicine in the treatment of immune-related adverse events of cancer immunotherapy. Journal of Traditional Chinese Medical Sciences, 2018, 5(4): 323-327. https://doi.org/10.1016/j.jtcms.2018.12.002

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Received: 24 July 2018
Revised: 12 December 2018
Accepted: 14 December 2018
Published: 16 December 2018
© 2019 Beijing University of Chinese Medicine. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).