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Full Length Article | Open Access

Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds

Chaoxin Wanga,b, Shuyuan Mina,b, Jinge Liuc, Bingchuan Liua,b, Bo Pengc, Caimei Wangd, Xiaolin Mad, Peng Wenc( ), Yufeng Zhenge( ), Yun Tiana,b( )
Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China
Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, China
Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
Beijing AKEC Medical Co., Ltd., Beijing 102200, China
School of Materials Science and Engineering, Peking University, Beijing 100871, China
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Abstract

Only a few studies have examined how pore geometry affects the mechanical characteristics, biological behavior, and degradation of additively manufactured biodegradable porous magnesium. In this work, the effects of pore geometry on mechanical qualities, degradation, and biological behavior were investigated using three typical porous architectures with the same porosity. The porous structures were found to satisfy bone tissue engineering requirements because they had sufficient degradation resistance and tunable compressive characteristics. All three types of magnesium alloy scaffolds exhibited good biocompatibility. Additionally, the magnesium alloy porous structures influenced the magnesium scaffold material degradation rate and the surrounding environment, impacting the osteogenic differentiation of bone mesenchymal stem cells and bone tissue regeneration. This work offers conceptual support for optimizing pore geometry to alter the mechanical and degradable characteristics of additively manufactured porous magnesium to meet therapeutic demands.

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Journal of Magnesium and Alloys
Pages 4509-4520

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Cite this article:
Wang C, Min S, Liu J, et al. Effect of pore geometry on properties of high-temperature oxidized additively manufactured magnesium scaffolds. Journal of Magnesium and Alloys, 2024, 12(11): 4509-4520. https://doi.org/10.1016/j.jma.2023.08.016

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Received: 14 April 2023
Revised: 08 June 2023
Accepted: 14 August 2023
Published: 19 September 2023
© 2024 Chongqing University.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) Peer review under responsibility of Chongqing University