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Adjuvanting a subunit novel variant IBDV vaccine to induce protective immunity

Gang Shu1, Jingyi Han1,2, Yuanling Huang2, Cong Huang2, Liping Kong3, Hongchang Li1,2, Lu Zhao2, Qijiang Tang2, Jia Li2, Yingnan Liu2, Jingyi Liu2, Hongjun Chen2, Zongyan Chen2( )
Department of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 625014, China
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China
SEPPIC (Shanghai) Chemical Specialities Co., Ltd., Shanghai 200041, China
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Highlights

  • Evaluated the safety and efficacy of subunit vaccine prepared with different adjuvants in chicks.

  • The vaccine prepared using the evaluated adjuvant has enhanced its protective effect against IBDV infection.

  • Gel P vaccine is the most convenient to prepare, and ISA 78 VG has better stability than other adjuvants.

References

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Journal of Integrative Agriculture (JIA)
Pages 2019-2023

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Cite this article:
Shu G, Han J, Huang Y, et al. Adjuvanting a subunit novel variant IBDV vaccine to induce protective immunity. Journal of Integrative Agriculture (JIA), 2025, 24(5): 2019-2023. https://doi.org/10.1016/j.jia.2024.12.007

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Received: 11 March 2024
Revised: 11 August 2024
Accepted: 27 October 2024
Published: 09 December 2024
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