AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
Powered by AMiner. Clicking this button will take you away from SciOpen.
Home Journal of Integrative Agriculture (JIA) Article
PDF (4.8 MB)
Cite
EndNote(RIS) BibTeX
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline

Preparation and characterization of monoclonal antibodies against the pp62 protein of African swine fever virus

Zhiyong Xiang1,2, Huan Ye1,2, Peng Gao1,2, Lei Zhou1,2, Xinna Ge1,2, Xin Guo1,2, Jun Han1,2, Yongning Zhang1,2( ), Hanchun Yang1,2( )
National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
Show Author Information

Highlights

  • Two mAbs (4B5-19-7 and 4C5-11-6) specifically recognizing the ASFV polyprotein pp62 were prepared, which can further recognize its mature proteins p15 and p35, respectively.

  • Heavy-chain CDR sequences of the two mAbs were different, while their light-chain CDR sequences were identical.

  • The epitopes recognized by 4B5-19-7 and 4C5-11-6 were located at amino acids 95–105 and 171–180 of pp62, respectively, and were highly conserved among ASFV strains of different genotypes.

References

【1】
【1】
 
 
Crossref Google Scholar
Journal of Integrative Agriculture (JIA)
Volume 24 Issue 6,
June 2025
Pages 2443-2447
DOI: 10.1016/j.jia.2024.11.020

{{item.num}}

Comments on this article

Go to comment

< Back to all reports

Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

Review Comment

Cite this Report
Close
Close
Cite this article:
Xiang Z, Ye H, Gao P, et al. Preparation and characterization of monoclonal antibodies against the pp62 protein of African swine fever virus. Journal of Integrative Agriculture (JIA), 2025, 24(6): 2443-2447. https://doi.org/10.1016/j.jia.2024.11.020

484

Views

14

Downloads

1

Crossref

2

Web of Science

1

Scopus

0

CSCD
Received: 22 July 2024
Revised: 18 September 2024
Accepted: 08 October 2024
Published: 06 November 2024
© 2025, Chinese Academy of Agricultural Sciences (CAAS). All rights reserved.