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Infectious Medicine 2023, 2(4): 273-282 https://doi.org/10.1016/j.imj.2023.11.003
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The awareness and acceptance of HPV vaccines among parents of primary and junior high school students in China: a meta-analysis

Show Author's Information Meimei Cuia,b,#,  Yun Wanga,#,  Zhen Liuc,  Congxiao Liud,  Tianhua Niue,  Dan Zhoua,f,  Ming Zhaoa,f,  Min Zhanga,f,  Jingjing Jiaa,f,  Limei Luoa( )
Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan 250014, China
Department of Pathology, Weifang Medical University, Weifang 261053, China
Qingzhou Maternal and Child Health Care Hospital, Weifang 262500, China
Jinan Huiwen Experimental School, Jinan 250000, China
Taian NO.2 Senior High School Shandong, Taian 271000, China
School of Public Health, Jiamusi University, Jiamusi 154007, China

# These authors contributed equally.

Keywords:
Meta-analysis, Vaccine, Acceptance, Human papillomavirus, Parents
Cite this article:
Cui M, Wang Y, Liu Z, et al. The awareness and acceptance of HPV vaccines among parents of primary and junior high school students in China: a meta-analysis. Infectious Medicine, 2023, 2(4): 273-282. https://doi.org/10.1016/j.imj.2023.11.003
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Abstract Full text Electronic supplementary material About this article

The awareness and acceptance of the human papillomavirus (HPV) vaccines among Chinese primary and junior high school students is limited. A meta-analysis was conducted to evaluate the awareness of HPV and HPV vaccines, as well as the acceptance of HPV vaccines, providing evidence-based strategies to promote HPV vaccination. Based on the databases of CNKI, Wanfang, VIP, PubMed, Embase, and Cochrane library, the literatures about the awareness of HPV and HPV vaccines, as well as the acceptance of HPV vaccines among parents of primary and junior high school students were collected from the inception to June 2023. Subgroup analysis was used to find the source of heterogeneity. Publication bias was evaluated using funnel plots and Egger’s test. Fifteen literatures with 21,853 participants were included. The pooled HPV awareness, HPV vaccine awareness and acceptance rates among parents of primary and junior high school students in China were 42.90% (95% CI: 33.34%–52.47%), 28.11% (95% CI: 18.20%–43.41%), and 55.29% (95% CI: 45.85%–64.36%), respectively. The survey period and the proportion of female parents were the heterogeneity in awareness of HPV and HPV vaccines, as well as acceptance of HPV vaccines by subgroup analysis. Additionally, regional distribution emerged as another significant source of heterogeneity in HPV vaccine acceptance. The primary cause for parents’ reluctance to vaccinate their children was theirs worries about the safety of the vaccines (66.21%). Though the awareness of HPV and its vaccines was low among parents of primary and junior high school students in China, the acceptance of HPV vaccines was relatively high. Strengthening health education and publicity was crucial to enhance awareness and acceptance, promoting HPV vaccination for effective cervical cancer prevention.


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Abstract
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Electronic supplementary material
About this article

The awareness and acceptance of HPV vaccines among parents of primary and junior high school students in China: a meta-analysis

Show Author's information Meimei Cuia,b,#, Yun Wanga,#, Zhen Liuc, Congxiao Liud, Tianhua Niue, Dan Zhoua,f, Ming Zhaoa,f, Min Zhanga,f, Jingjing Jiaa,f, Limei Luoa( )
Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan 250014, China
Department of Pathology, Weifang Medical University, Weifang 261053, China
Qingzhou Maternal and Child Health Care Hospital, Weifang 262500, China
Jinan Huiwen Experimental School, Jinan 250000, China
Taian NO.2 Senior High School Shandong, Taian 271000, China
School of Public Health, Jiamusi University, Jiamusi 154007, China

# These authors contributed equally.

Highlights

• The pooled HPV awareness, HPV vaccine awareness and acceptance rates among parents of primary and junior high school students in China were 42.90%, 28.11% and 55.29%, respectively.

• The awareness of HPV and HPV vaccines among parents of primary and junior high school students in China was relatively low, but the acceptance of HPV vaccines was high.

• The main factors affecting parental HPV vaccines acceptance were vaccine safety, vaccine effectiveness, parental awareness, and children's age.

Abstract

The awareness and acceptance of the human papillomavirus (HPV) vaccines among Chinese primary and junior high school students is limited. A meta-analysis was conducted to evaluate the awareness of HPV and HPV vaccines, as well as the acceptance of HPV vaccines, providing evidence-based strategies to promote HPV vaccination. Based on the databases of CNKI, Wanfang, VIP, PubMed, Embase, and Cochrane library, the literatures about the awareness of HPV and HPV vaccines, as well as the acceptance of HPV vaccines among parents of primary and junior high school students were collected from the inception to June 2023. Subgroup analysis was used to find the source of heterogeneity. Publication bias was evaluated using funnel plots and Egger’s test. Fifteen literatures with 21,853 participants were included. The pooled HPV awareness, HPV vaccine awareness and acceptance rates among parents of primary and junior high school students in China were 42.90% (95% CI: 33.34%–52.47%), 28.11% (95% CI: 18.20%–43.41%), and 55.29% (95% CI: 45.85%–64.36%), respectively. The survey period and the proportion of female parents were the heterogeneity in awareness of HPV and HPV vaccines, as well as acceptance of HPV vaccines by subgroup analysis. Additionally, regional distribution emerged as another significant source of heterogeneity in HPV vaccine acceptance. The primary cause for parents’ reluctance to vaccinate their children was theirs worries about the safety of the vaccines (66.21%). Though the awareness of HPV and its vaccines was low among parents of primary and junior high school students in China, the acceptance of HPV vaccines was relatively high. Strengthening health education and publicity was crucial to enhance awareness and acceptance, promoting HPV vaccination for effective cervical cancer prevention.

Keywords: Meta-analysis, Vaccine, Acceptance, Human papillomavirus, Parents

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Publication history

Received: 15 August 2023
Revised: 09 October 2023
Accepted: 10 November 2023
Published: 17 November 2023
Issue date: December 2023

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© 2023 The Author(s). Tsinghua University Press.

Acknowledgements

Thank you for Pro Huiju Han for the initial comments on the paper and for editing the final draft.

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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