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Case Report | Open Access

Bacteremia complicated with pneumonia caused by Corynebacterium diphtheriae

Xiaojun Zhoua,1Xuebing Wangb,1Hua WuaMeihui HuangaShaoling WangcXuming Wanga( )Haijian Zhoub( )
Department of Clinical Laboratory, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, 570311, China
State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, 102206, China
Hainan Center for Disease Control and Prevention, Haikou, 570203, China

1 These authors contributed equally to this work.

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Abstract

Due to the use of vaccines, infections caused by Corynebacterium diphtheriae are now rare. Here we describe a case of bacteremia complicated with pneumonia caused by C. diphtheriae in a 69-year-old male patient. The patient presented at the emergency department with a 2 days history of fever of unknown origin. Subsequent examinations revealed pneumonia and bacteremia. Non-toxigenic C. diphtheriae strains were isolated from blood and sputum. The patient had antimicrobial therapy with good improvement. We highlight the important role of C. diphtheriae in causing bacteremia and pneumonia, and its accurate and timely diagnosis is needed to avoid poor visual outcomes.

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Infectious Medicine
Pages 276-280

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Cite this article:
Zhou X, Wang X, Wu H, et al. Bacteremia complicated with pneumonia caused by Corynebacterium diphtheriae. Infectious Medicine, 2022, 1(4): 276-280. https://doi.org/10.1016/j.imj.2022.11.002

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Received: 09 June 2022
Revised: 10 October 2022
Accepted: 14 November 2022
Published: 18 November 2022
© 2022 The Authors. Published by Elsevier Ltd on behalf of Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)