Journal Home > Volume 1 , Issue 2
Infectious Medicine 2022, 1(2): 103-112 https://doi.org/10.1016/j.imj.2022.06.005
Original Article | Open Access | Issue | Published: 26 June 2022

Mapping the intersection of nanotechnology and SARS-CoV-2/COVID-19: A bibliometric analysis

Show Author's Information Xuejuan Zhanga,1,  Mengqin Guoa,1,  Zhengwei Huanga( ),  Ying Huanga,  Chuanbin Wua,  Xin Panb
College of Pharmacy, Jinan University, Guangzhou 510632, China
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China

1 These authors contributed equally to this work.

Keywords:
COVID-19, SARS-CoV-2, Web of Science, Bibiometric analysis, Nano technology
Cite this article:
Zhang X, Guo M, Huang Z, et al. Mapping the intersection of nanotechnology and SARS-CoV-2/COVID-19: A bibliometric analysis. Infectious Medicine, 2022, 1(2): 103-112. https://doi.org/10.1016/j.imj.2022.06.005
Download citation
EndNote(RIS)
BibTeX

534

Views

9

Downloads

Citations

3

Crossref

N/A

WoS

5

Scopus

N/A

CSCD

Abstract Full text Electronic supplementary material About this article
Background

Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has imposed great medical and economic burdens on human society, and nanotechnology is a promising technique for managing the ongoing COVID-19 pandemic. To drive further studies on anti-COVID-19 nanotechnology, this paper provides an analysis, from a bibliometric perspective, of the intersection of nanotechnology and SARS-CoV-2/COVID-19.

Methods

We analyzed the 2585 publications on nanotechnology and SARS-CoV-2/COVID-19 included in the Web of Science Core Collection from January 2019 to March 2022 to determine the bibliometric landscape. The basic bibliometric characteristics are summarized in this article.

Results

Our bibliometric analysis revealed that the intersection between nanotechnology and SARS-CoV-2/COVID-19 is a cutting-edge field in the science community and that the related studies were multidisciplinary in nature. Studies on the structural basis of SARS-CoV-2, SARS-CoV-2 detection assays, and mRNA vaccines against COVID-19 provided the development foundation for this field.

Conclusions

The current research focuses are the development of nanomaterial-based vaccines and SARS-CoV-2 detection methods, and the design of nanomedicines carrying SARS-CoV-2 inhibitors is a relatively burgeoning frontier. In summary, this bibliometric analysis of the intersection of nanotechnology and SARS-CoV-2/COVID-19 highlights the current research focuses of this field to inspire future studies on anti-COVID-19 nanotechnologies.


menu
Abstract
Full text
Outline
Electronic supplementary material
About this article

Mapping the intersection of nanotechnology and SARS-CoV-2/COVID-19: A bibliometric analysis

Show Author's information Xuejuan Zhanga,1, Mengqin Guoa,1, Zhengwei Huanga( ), Ying Huanga, Chuanbin Wua, Xin Panb
College of Pharmacy, Jinan University, Guangzhou 510632, China
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China

1 These authors contributed equally to this work.

Abstract

Background

Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has imposed great medical and economic burdens on human society, and nanotechnology is a promising technique for managing the ongoing COVID-19 pandemic. To drive further studies on anti-COVID-19 nanotechnology, this paper provides an analysis, from a bibliometric perspective, of the intersection of nanotechnology and SARS-CoV-2/COVID-19.

Methods

We analyzed the 2585 publications on nanotechnology and SARS-CoV-2/COVID-19 included in the Web of Science Core Collection from January 2019 to March 2022 to determine the bibliometric landscape. The basic bibliometric characteristics are summarized in this article.

Results

Our bibliometric analysis revealed that the intersection between nanotechnology and SARS-CoV-2/COVID-19 is a cutting-edge field in the science community and that the related studies were multidisciplinary in nature. Studies on the structural basis of SARS-CoV-2, SARS-CoV-2 detection assays, and mRNA vaccines against COVID-19 provided the development foundation for this field.

Conclusions

The current research focuses are the development of nanomaterial-based vaccines and SARS-CoV-2 detection methods, and the design of nanomedicines carrying SARS-CoV-2 inhibitors is a relatively burgeoning frontier. In summary, this bibliometric analysis of the intersection of nanotechnology and SARS-CoV-2/COVID-19 highlights the current research focuses of this field to inspire future studies on anti-COVID-19 nanotechnologies.

Keywords: COVID-19, SARS-CoV-2, Web of Science, Bibiometric analysis, Nano technology

References(61)

[1]

K. Yuki, M. Fujiogi, S. Koutsogiannaki, COVID-19 pathophysiology: a review, Clin Immunol 215 (2020) 108427.
DOI Google Scholar
[2]

Y. Shi, G. Wang, X. -p. Cai, et al., An overview of COVID-19, J Zhejiang Univ-SCIENCE B 21 (2020) 343–360.
DOI Google Scholar
[3]

T.K. Burki, Omicron variant and booster COVID-19 vaccines, Lancet Respir Med 10 (2022) e17.
DOI Google Scholar
[4]

M. Sudhakar, S.B. Winfred, G. Meiyazhagan, et al., Mechanisms contributing to adverse outcomes of COVID-19 in obesity, Mol Cell Biochem 477 (2022) 1–39.
DOI Google Scholar
[5]

Y. Yin, W. Su, J. Zhang, et al., Separable microneedle patch to protect and deliver DNA nanovaccines against COVID-19, Acs Nano 15 (2021) 14347–14359.
DOI Google Scholar
[6]

K. Wu, R. Saha, D.Q. Su, et al., Magnetic-nanosensor-based virus and pathogen detection strategies before and during COVID-19, Acs Appl Nano Mater 3 (2020) 9560–9580.
DOI Google Scholar
[7]

V. Thakur, R.K. Ratho, J.J. Panda, Respiratory delivery of favipiravir-tocilizumab combination through mucoadhesive protein-lipidic nanovesicles: prospective therapeutics against COVID-19, Virus Dis 32 (2021) 131–136.
DOI Google Scholar
[8]

L. Mazzola, Commercializing nanotechnology, Nat Biotechnol 21 (2003) 1137–1143.
DOI Google Scholar
[9]

P. Kokol, H.B. Vosner, J. Zavrsnik, Application of bibliometrics in medicine: a historical bibliometrics analysis, Health Info Libr J 38 (2021) 125–138.
DOI Google Scholar
[10]

Y.T. Yu, Y.J. Li, Z.H. Zhang, et al., A bibliometric analysis using VOSviewer of publications on COVID-19, Ann Transl Med 8 (13) (2020).
DOI Google Scholar
[11]

H. ElHawary, A. Salimi, N. Diab, et al., Bibliometric analysis of early COVID-19 research: the top 50 cited papers, Infect Dis (Auckl) 13 (2020) 1178633720962935.
DOI Google Scholar
[12]

R.K. Farooq, S.U. Rehman, M. Ashiq, et al., Bibliometric analysis of coronavirus disease (COVID-19) literature published in Web of Science 2019-2020, J Fam Community Med 28 (2021) 1–7.
DOI Google Scholar
[13]

P. Wang, D. Tian, Bibliometric analysis of global scientific research on COVID-19, J Biosaf Biosecur 3 (2021) 4–9.
DOI Google Scholar
[14]

J.C. Fan, Y. Gao, N. Zhao, et al., Bibliometric analysis on COVID-19: a comparison of research between English and Chinese studies, Front Public Health 8 (2020) 477.
DOI Google Scholar
[15]

J. Jacimovic, A. Jakovljevic, V. Nagendrababu, et al., A bibliometric analysis of the dental scientific literature on COVID-19, Clin Oral Invest 25 (2021) 6171–6183.
DOI Google Scholar
[16]

P. Mansoori, 50 years of Iranian clinical, biomedical, and public health research: a bibliometric analysis of the Web of Science Core Collection (1965-2014), J Glob Health 8 (2) (2018).
DOI Google Scholar
[17]

M. Ciotti, S. Angeletti, M. Minieri, et al., COVID-19 outbreak: an overview, Chemotherapy 64 (2020) 215–223.
DOI Google Scholar
[18]

L. Xie, Z.H. Chen, H.L. Wang, et al., Bibliometric and visualized analysis of scientific publications on atlantoaxial spine surgery based on Web of Science and VOSviewer, World Neurosurg 137 (2020) 435.
DOI Google Scholar
[19]

Y.L. Song, F.K. Zhao, Bibliometric analysis of metabolic surgery for type 2 diabetes: current status and future prospects, Updates Surg 74 (2) (2022) 697–707.
DOI Google Scholar
[20]

Q.X. Zhang, H. Li, Y. Zhao, et al., Surgical procedures for hip joint preservation for osteonecrosis of the femoral head: a bibliometric analysis, Biomed Res Int (2021) 2021.
DOI Google Scholar
[21]

A. Tlili, F. Altinay, R. Huang, et al., Are we there yet? A systematic literature review of Open Educational Resources in Africa: a combined content and bibliometric analysis, Plos one 17 (2022) e0262615.
DOI Google Scholar
[22]

Y.Z. Ai, Y.X. Xing, L.M. Yan, et al., Atrial fibrillation and depression: a bibliometric analysis from 2001 to 2021, Front Cardiovasc Med 9 (2022).
DOI Google Scholar
[23]

S. Tonen-Wolyec, D.M.M. Lupaka, S. Batina-Agasa, et al., Review of authorship for COVID-19 research conducted during the 2020 first-wave epidemic in Africa reveals emergence of promising African biomedical research and persisting asymmetry of international collaborations, Trop Med Int Health 27 (2022) 137–148.
DOI Google Scholar
[24]
O. Păduraru, A. Moroșanu, C. Ș. Păduraru, et al., Healthcare management: a bibliometric analysis based on the citations of research articles published between 1967 and 2020, in: healthcare, MDPI 10 (3) (2022) 555.
DOI
[25]

X.L. Yang, H. Yin, L.S. Peng, et al., The global status and trends of enteropeptidase: a bibliometric study, Front Med-Lausanne 9 (2022).
DOI Google Scholar
[26]

L.P. Tan, Mapping the social entrepreneurship research: Bibliographic coupling, co-citation and co-word analyses, Cogent Bus Manag 8 (1) (2021) 1896885.
DOI Google Scholar
[27]

K.W. Boyack, R. Klavans, Co-citation analysis, bibliographic coupling, and direct citation: which citation approach represents the research front most accurately? J Am Soc Inf Sci Tec 61 (2010) 2389–2404.
DOI Google Scholar
[28]

D. Wrapp, N.S. Wang, K.S. Corbett, et al., Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation, Science 367 (2020) 1260.
DOI Google Scholar
[29]

J. Lan, J.W. Ge, J.F. Yu, et al., Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor, Nature 581 (2020) 215.
DOI Google Scholar
[30]

R.H. Yan, Y.Y. Zhang, Y.N. Li, et al., Structural basis for the recognition of SARS–CoV-2 by full-length human ACE2, Science 367 (2020) 1444.
DOI Google Scholar
[31]

G. Seo, G. Lee, M.J. Kim, et al., Rapid detection of COVID-19 causative virus (SARS–CoV-2) in human nasopharyngeal swab specimens using field-effect transistor-based biosensor (vol 14, pg 5135, 2020), Acs Nano 14 (2020) 12257–12258.
DOI Google Scholar
[32]

J.P. Broughton, X.D. Deng, G.X. Yu, et al., CRISPR-Cas12-based detection of SARS–CoV-2, Nat Biotechnol 38 (2020) 870.
DOI Google Scholar
[33]

B. Udugama, P. Kadhiresan, H.N. Kozlowski, et al., Diagnosing COVID-19: the disease and tools for detection, Acs Nano 14 (2020) 3822–3835.
DOI Google Scholar
[34]

L.R. Baden, H.M. El Sahly, B. Essink, et al., Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine, New Engl J Med 384 (2021) 403–416.
DOI Google Scholar
[35]

L.A. Jackson, E.J. Anderson, N.G. Rouphael, et al., An mRNA vaccine against SARS–CoV-2-preliminary report, New Engl J Med 383 (2020) 1920–1931.
DOI Google Scholar
[36]

J.N. Vergnes, Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine, New Engl J Med 384 (2021) 1577.
DOI Google Scholar
[37]

N. Pardi, M.J. Hogan, F.W. Porter, et al., mRNA vaccines - a new era in vaccinology, Nat Rev Drug Discov 17 (2018) 261–279.
DOI Google Scholar
[38]

F.N. Maria Helha, Y.P. Wang, Trends in complementary and alternative medicine for the treatment of common mental disorders: a bibliometric analysis of two decades, Complement Ther Clin Pract 46 (2022) 101531.
DOI Google Scholar
[39]

D. Kim, J.Y. Lee, J.S. Yang, et al., The architecture of SARS-CoV-2 transcriptome, Cell 181 (2020) 914–921 e910.
DOI Google Scholar
[40]

Z. Lv, Y.Q. Deng, Q. Ye, et al., Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody, Science 369 (2020) 1505–1509.
DOI Google Scholar
[41]

Y. Han, P. Kral, Computational design of ACE2-based peptide inhibitors of SARS–CoV-2, Acs Nano 14 (2020) 5143–5147.
DOI Google Scholar
[42]

P.T. Heath, E.P. Galiza, D.N. Baxter, et al., Safety and efficacy of NVX-CoV2373 Covid-19 vaccine, N Engl J Med 385 (2021) 1172–1183.
DOI Google Scholar
[43]

V. Shinde, S. Bhikha, Z. Hoosain, et al., Efficacy of NVX-CoV2373 Covid-19 vaccine against the B. 1.351 variant, N Engl J Med 384 (2021) 1899–1909.
DOI Google Scholar
[44]

H.M. Wahedi, S. Ahmad, S.W. Abbasi, Stilbene-based natural compounds as promising drug candidates against COVID-19, J Biomol Struct Dyn 39 (2021) 3225–3234.
DOI Google Scholar
[45]

A.L.P. Silva, J.C. Prata, T.R. Walker, et al., Increased plastic pollution due to COVID-19 pandemic: challenges and recommendations, Chem Eng J 405 (2021) 126683.
DOI Google Scholar
[46]

Z. Li, Y. Wang, L. Li, et al., A bibliometric analysis of the cause of sudden unexplained death in forensic medicine: research trends, hot spots and prospects, Comput Biol Med 144 (2022) 105330.
DOI Google Scholar
[47]

C. Peng, L. Kuang, J. Zhao, et al., Bibliometric and visualized analysis of ocular drug delivery from 2001 to 2020, J Control Release 345 (2022) 625–645.
DOI Google Scholar
[48]

F. Yu, L.T. Lau, M. Fok, et al., COVID-19 delta variants-current status and implications as of August 2021, Precis Clin Med 4 (2021) 287–292.
DOI Google Scholar
[49]

S.A. Madhi, G. Kwatra, J.E. Myers, et al., Population immunity and Covid-19 severity with omicron variant in South Africa, New Engl J Med 386 (14) (2022) 1314–1326.
DOI Google Scholar
[50]

J.L. Huang, Y.B. Ding, J.W. Yao, et al., Nasal nanovaccines for SARS-CoV-2 to address COVID-19, Vaccines-Basel 10 (3) (2022) 405.
DOI Google Scholar
[51]

M. Alafeef, P. Moitra, K. Dighe, et al., RNA-extraction-free nano-amplified colorimetric test for point-of-care clinical diagnosis of COVID-19, Nat Protoc 16 (2021) 3141.
DOI Google Scholar
[52]

X.H. Jin, K.I. Zheng, K.H. Pan, et al., COVID-19 in a patient with chronic lymphocytic leukaemia, Lancet Haematol 7 (2020) E351–E352.
DOI Google Scholar
[53]

J.S. Khalili, H. Zhu, N.S.A. Mak, et al., Novel coronavirus treatment with ribavirin: groundwork for an evaluation concerning COVID-19, J Med Virol 92 (2020) 740–746.
DOI Google Scholar
[54]

W.Y. Chen, M. Yao, Z.X. Fang, et al., A study on clinical effect of Arbidol combined with adjuvant therapy on COVID-19, J Med Virol 92 (2020) 2702–2708.
DOI Google Scholar
[55]

J.J. Gao, Z.X. Tian, X. Yang, Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies, Biosci Trends 14 (2020) 72–73.
DOI Google Scholar
[56]

W. Ren, P. Liang, Y. Ma, et al., Research progress of traditional Chinese medicine against COVID-19, Biomed Pharmacother 137 (2021) 111310.
DOI Google Scholar
[57]

X. Pan, N. Wu, S. Tian, et al., Inhalable MOF-derived nanoparticles for sonodynamic therapy of bacterial pneumonia, Adv Funct Mater 32 (25) (2022) 2112145.
DOI Google Scholar
[58]

F. Mayta-Tovalino, Bibliometric analyses of global scholarly output in dentistry related to COVID-19, J Int Soc Prev Commu 12 (2022) 100–108.
Google Scholar
[59]

N. Giannetta, S. Dionisi, M. Tonello, et al., A worldwide bibliometric analysis of published literature on medication errors, J Patient Saf 18 (2022) 201–209.
DOI Google Scholar
[60]

D. El Masri, B. Alsaayed, J. El Masri, et al., Contribution of Arab countries to familial mediterranean fever research: a PubMed-based bibliometric analysis, Rheumatol Int 42 (2022) 95–100.
DOI Google Scholar
[61]

P. Ahmad, J.A. Asif, M.K. Alam, et al., A bibliometric analysis of Periodontology 2000, Periodontol 82 (2020) 286–297 2000.
DOI Google Scholar
File
imj-1-2-103_ESM1.docx (32.8 MB)
Publication history
Copyright
Acknowledgements
Rights and permissions

Publication history

Received: 15 April 2022
Revised: 09 June 2022
Accepted: 14 June 2022
Published: 26 June 2022
Issue date: June 2022

Copyright

© 2022 The Author(s). Published by Elsevier Ltd on behalf of Tsinghua University Press.

Acknowledgements

Acknowledgements

We thank Mr. Jiajun Chen from Jinan University for helping to polish the manuscript.

Rights and permissions

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)

Return