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Letter | Open Access

Dual strategies for durable antibodies against SARS-CoV-2: Immune trajectories and viral fitness constraints

Pengyue Gao1,2, Linh Nguyen2, André Costa Lobato3, George Fu Gao2, Zhou Tong2( )
Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, China
CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
Center for Technology Development in Health, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil
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hLife
Volume 4 Issue 2,
February 2026
Pages 123-126
DOI: 10.1016/j.hlife.2025.10.002

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Cite this article:
Gao P, Nguyen L, Lobato AC, et al. Dual strategies for durable antibodies against SARS-CoV-2: Immune trajectories and viral fitness constraints. hLife, 2026, 4(2): 123-126. https://doi.org/10.1016/j.hlife.2025.10.002

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Received: 21 August 2025
Revised: 29 September 2025
Accepted: 10 October 2025
Published: 01 February 2026
© 2025

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).