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Commentary | Open Access

Move without moving: Kidney-produced betaine mimics exercise to slow aging

Yue Li1,#, Xinxin Tang1,#, Yinkun Fu1, Ming He1,2( )
Institute for Translational Medicine on Cell Fate and Disease, Shanghai Ninth People’s Hospital, Key Laboratory of Cell Differentiation and Apoptosis of National Ministry of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Orthopaedics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

#These authors contributed equally to this work

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hLife
Volume 4 Issue 3,
March 2026
Pages 132-134
DOI: 10.1016/j.hlife.2025.06.007

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Cite this article:
Li Y, Tang X, Fu Y, et al. Move without moving: Kidney-produced betaine mimics exercise to slow aging. hLife, 2026, 4(3): 132-134. https://doi.org/10.1016/j.hlife.2025.06.007

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Received: 16 June 2025
Revised: 20 June 2025
Accepted: 21 June 2025
Published: 01 March 2026
© 2025 The Author(s).

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).