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Letter | Open Access

Rational design of human CD26 receptor for a strong neutralizing ability against MjHKU4r-CoV-1 and MERS-CoV

Yalei Zhang1,2,#Mingxiong Tian1,#Yanjun Han1,2,#Junqing Sun3,4Wenwei Li5Chongzhi Bai6( )Chao Su1( )Pengcheng Han1( )
Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Zhongda Hospital, Advanced Institute for Life and Health, Southeast University, Jiangsu, China
College of Veterinary Medicine, Shanxi Agricultural University, Shanxi, China
Innovative Vaccine and Immunotherapy Research Center, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China
State Key Laboratory of Transvascular Implantation Devices, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, China
Shanxi Academy of Advanced Research and Innovation, Shanxi, China
Central Laboratory, Shanxi Province Hospital of Traditional Chinese Medicine, Shanxi, China

#These authors contributed equally to this work

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hLife
Pages 565-568

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Cite this article:
Zhang Y, Tian M, Han Y, et al. Rational design of human CD26 receptor for a strong neutralizing ability against MjHKU4r-CoV-1 and MERS-CoV. hLife, 2025, 3(11): 565-568. https://doi.org/10.1016/j.hlife.2025.05.005

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Received: 01 April 2025
Revised: 30 April 2025
Accepted: 16 May 2025
Published: 01 November 2025
© 2025 The Author(s).

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).