AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
PDF (200.1 KB)
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Review Article | Open Access

Research progress on risk stratification warning models for early hematoma expansion and poor outcome in intracerebral hemorrhage: A narrative review

Shuqiang Zhanga,b,c,1Tao Jianga,1Keqiong YandYanling ZhangaXiao HuaXiaoyan TangaWensong Yangb,c( )Peng Xieb,c( )
Department of Radiology, Chongqing University FuLing Hospital, Chongqing 408000, China
Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
NHC Key Laboratory of Diagnosis and Treatment on Chongqing 400016, Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, China
Department of Neurology, Chongqing University FuLing Hospital, Chongqing 408000, China

1 These authors contributed equally to this work.

Peer review under the responsibility of Editorial Board of Brain Hemorrhages.

Show Author Information

Abstract

Objective

This review explores recent advances in risk stratification systems for early hematoma expansion (HE), focusing on predictive models using CTA, NCCT, radiomics, and artificial intelligence to enhance accuracy and clinical utility. The study analyzes literature on CTA spot signs, NCCT imaging features, and radiomics combined with machine learning for hematoma expansion prediction. It compares traditional biomarkers with artificial intelligence-driven models.

Methods

A narrative review was performed to synthesize the available literature and explore the predictive value of CTA spot signs, NCCT imaging features, and radiomics combined with machine learning for hematoma expansion and outcomes.

Results

Integrating multimodal imaging and artificial intelligence significantly enhances HE prediction. Future work should focus on multicenter validation and standardized models to optimize personalized treatment and improve intracerebral hemorrhage outcomes.

Conclusion

Intelligent risk stratification systems, incorporating multimodal imaging and artificial intelligence, enhance hematoma expansion prediction and clinical utility. Future research could prioritize multicenter validation, standardization of models, and the development of personalized treatment strategies to ultimately improve outcomes for ICH patients.

References

【1】
【1】
 
 
Brain Hemorrhages
Pages 49-55

{{item.num}}

Comments on this article

Go to comment

< Back to all reports

Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

Review Comment

Close
Close
Cite this article:
Zhang S, Jiang T, Yan K, et al. Research progress on risk stratification warning models for early hematoma expansion and poor outcome in intracerebral hemorrhage: A narrative review. Brain Hemorrhages, 2026, 7(1): 49-55. https://doi.org/10.1016/j.hest.2025.11.004

2

Views

0

Downloads

0

Crossref

0

Web of Science

0

Scopus

Received: 01 June 2025
Revised: 06 November 2025
Accepted: 12 November 2025
Published: 14 November 2025
© 2025 International Hemorrhagic Stroke Association.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).