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Research Article | Open Access

IRRAflow active irrigation and drainage system: A glimpse into the future of cerebrospinal fluid shunts

Saif D. SalmanaRabih G. TawkbKrishnan RavindraneDaniel A. TonettihNicholas BrandmeirfBehnam Rezai JahromigBabak JahromiiRichard W. ByrnebWilliam D. Freemanb,c,d( )
Department of Neurologic Surgery, Neurology and Critical Care, Mayo Clinic, Jacksonville, FL, USA
Department of Neurologic Surgery, Mayo Clinic, Jacksonville, FL, USA
Department of Critical Care Medicine, Mayo Clinic, Jacksonville, FL, USA
Department of Neurology, Mayo Clinic, Jacksonville, FL, USA
Department of Neurologic Surgery, Mayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Jacksonville, FL, USA
Department of Neurosurgery, Rockefeller Neuroscience Institute, West Virginia University School of Medicine, Morgantown, WV, USA
Department of Neurosurgery, University of Helsinki, Helsinki, Finland
Department of Neurosurgery, Cooper University Hospital, NJ, USA
Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
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Abstract

Chronic hydrocephalus after subarachnoid hemorrhage may become inevitable, necessitating a permanent cerebrospinal fluid shunt. We report a 40-year-old woman with SAH and a CHESS score of 6. We implemented the IRRAflow active irrigation and drainage system which expedited hemorrhage clearance in 4 days compared to one or two weeks longer with standard external ventricular drains. This system reduced the inflammatory load and preserved the arachnoid granulations, which are responsible for CSF resorption. Further, expedited recanalization of the fourth ventricle prevented an exponential increase in intracranial pressure. Collectively, these factors prevented CSF shunt dependency.

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Brain Hemorrhages
Pages 339-342

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Cite this article:
Salman SD, Tawk RG, Ravindran K, et al. IRRAflow active irrigation and drainage system: A glimpse into the future of cerebrospinal fluid shunts. Brain Hemorrhages, 2025, 6(6): 339-342. https://doi.org/10.1016/j.hest.2025.10.002

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Received: 05 October 2025
Revised: 20 October 2025
Accepted: 23 October 2025
Published: 02 November 2025
© 2025 International Hemorrhagic Stroke Association.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).