Predictors of risk of intracerebral hemorrhage after intracranial artery intervention in intracranial atherosclerotic stenosis patients

To investigate the relationship between clinical characters of intracranial atherosclerotic stenosis patients and occurrence of cerebral hemorrhage after intracranial artery intervention. Clinical data of total 501 patients who underwent endovascular therapy for ischemic stroke or transient ischemic attack were retrospectively reviewed. Median (interquartile range, IQR) of the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology (ASITN/SIR) collateral score was higher in intracerebral hemorrhage (ICH) group (P < 0.001). Cerebral blood flow (CBF) reducing, cerebral blood volume (CBV) reducing, time to peak (TTP) delaying and mean transit time (MTT) delaying in the lesion side comparing the contralateral side were higher in ICH group (P = 0.018, P = 0.046, P = 0.012, P = 0.038). ASITN/SIR ≤ 2, CBF reducing ≥ 40%, CBV reducing ≥ 30%, TTP delaying ≥ 2 s, MTT delaying ≥ 1 s, infarction volume ≥ 20 mL were probably the independent predictors of ICH following endovascular therapy.