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Rapid Communication | Open Access

GBM-Dx SIGNAL: Blood transcriptomics complementing neuroimaging to differentiate glioblastoma recurrence from treatment effects

Dan Qia,b( ), James Murchisonc, Ekokobe Fonkemd, Jason H. Huanga,b, Erxi Wua,b,e,f( )
Department of Neurosurgery and Neuroscience Institute, Baylor Scott & White Health, Temple, TX 76508, USA
Department of Neurosurgery, Baylor College of Medicine, Temple, TX 76508, USA
Department of Diagnostic Radiology, Baylor Scott & White Medical Center, Temple, TX 76508, USA
Department of Neurology and Banner MD Anderson Cancer Center, University of Arizona, Phoenix, AZ 85006, USA
College of Medicine and College of Pharmacy, Texas A&M University, College Station, TX 77843, USA
Livestrong Cancer Institutes and Department of Internal Medicine, Dell Medical School, The University of Texas at Austin, Austin, TX 78712, USA

Peer review under the responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 13 Issue 5,
September 2026
DOI: 10.1016/j.gendis.2026.102029

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Cite this article:
Qi D, Murchison J, Fonkem E, et al. GBM-Dx SIGNAL: Blood transcriptomics complementing neuroimaging to differentiate glioblastoma recurrence from treatment effects. Genes & Diseases, 2026, 13(5). https://doi.org/10.1016/j.gendis.2026.102029

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Received: 21 September 2025
Published: 06 January 2026
© 2026 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).