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Rapid Communication | Open Access

RFX3 loss disrupts non-coding RNA networks in iPSC-derived pancreatic progenitors

Noura Aldousa,b,d, Aldana Alnesfa,b,d, Ahmed K. Elsayeda,b, Bushra Yasin Abohalawab,c, Nehad M. Alajezb,c, Essam M. Abdelalima,b( )
Pluripotent Stem Cell Disease Modelling Lab, Translational Medicine Department, Research Branch, Sidra Medicine, Doha 26999, Qatar
College of Health and Life Sciences, Hamad Bin Khalifa University (HBKU), Qatar Foundation (QF), Doha 34110, Qatar
Translational Oncology Research Centre (TORC), Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation (QF), Doha 34110, Qatar

d These authors contributed equally to this work and shared the first authorship.

Peer review under the responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 13 Issue 4,
July 2026
DOI: 10.1016/j.gendis.2025.101959

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Cite this article:
Aldous N, Alnesf A, Elsayed AK, et al. RFX3 loss disrupts non-coding RNA networks in iPSC-derived pancreatic progenitors. Genes & Diseases, 2026, 13(4). https://doi.org/10.1016/j.gendis.2025.101959

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Received: 07 July 2025
Published: 27 November 2025
© 2025 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).