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Commentary | Open Access

Epigenetic insights into minimal residual disease detection in cancer

Lingao Jua,b,g, Gang Wanga,c,g, Zilin Xua,d,g, Wan Xianga, Hongwei Penga, Mengxue Yua, Shenjuan Lib, Yi Zhange,f, Kaiyu Qiana,c( ), Yu Xiaoa,b,d( )
Department of Biological Repositories, Human Genetic Resources Preservation Center of Hubei Province, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China
Hubei Key Laboratory of Urological Diseases, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China
Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China
Department of Laboratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China
Euler Technology, ZGC Life Sciences Park, Beijing 102206, China
High Performance Computing Center, The Peking-Tsinghua College of Life Sciences, Peking University, Beijing 100091, China

g These authors contributed equally to this work.

Peer review under the responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 13 Issue 3,
May 2026
DOI: 10.1016/j.gendis.2025.101830

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Cite this article:
Ju L, Wang G, Xu Z, et al. Epigenetic insights into minimal residual disease detection in cancer. Genes & Diseases, 2026, 13(3). https://doi.org/10.1016/j.gendis.2025.101830

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Received: 01 March 2025
Accepted: 22 July 2025
Published: 01 May 2026
© 2025 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).