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Rapid Communication | Open Access

Single-cell transcriptome profiling reveals altered neural crest cell dynamics and novel biomarkers in EDNRB mutant mice with Hirschsprung's disease phenotype

Minhao Sun, Jafari Halima, Yidan Li, Jiangtian Su, Ge Yang, Jiajun Guo, Qiwen Yang, Ruihua Dang( )
College of Animal Science and Technology, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 13 Issue 1,
January 2026
DOI: 10.1016/j.gendis.2025.101765

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Sun M, Halima J, Li Y, et al. Single-cell transcriptome profiling reveals altered neural crest cell dynamics and novel biomarkers in EDNRB mutant mice with Hirschsprung's disease phenotype. Genes & Diseases, 2026, 13(1). https://doi.org/10.1016/j.gendis.2025.101765

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Received: 02 October 2023
Published: 08 July 2025
© 2025 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).